Results 31 to 40 of about 663,482 (304)

Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms [PDF]

, 2006
Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. Three of them, Asp, Glu, and (oxidized) Cys, function through their conjugation to Arg, one of destabilizing N-terminal residues that are recognized directly by
Brower, Christopher S., Davydov, Ilia V., Hu, Rong-Gui, Kwon, Yong Tae, Sheng, Jun, Varshavsky, Alexander, Wang, Haiqing, Zhou, Jianmin   +7 more
core   +2 more sources

Functional differences of iodinated obestatin peptides: in vitro metabolic stability profile [PDF]

, 2010
Peptides are small polymers of 50 amino acids, situated between organic molecules and proteins. Most peptides perform a biochemical-physical function and are therefore considered as potential drugs.
De Spiegeleer, Bart, Van Dorpe, Sylvia, Wallez, Ingeborg   +2 more
core   +1 more source

O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease. [PDF]

, 2015
Several aggregation-prone proteins associated with neurodegenerative diseases can be modified by O-linked N-acetyl-glucosamine (O-GlcNAc) in vivo. One of these proteins, α-synuclein, is a toxic aggregating protein associated with synucleinopathies ...
Ambroso, Mark R, Arnold, Don B, Langen, Ralf, Lewis, Yuka E, Lin, Yu Hsuan, Marotta, Nicholas P, Pratt, Matthew R, Roth, Maxwell T, Zaro, Balyn W   +8 more
core   +2 more sources

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Per- and Polyfluoroalkyl Substance Levels in Commercial and Home-Produced Eggs in Croatia

Foods
The aim of this study was to measure per- and polyfluoroalkyl substance (PFAS) levels in eggs collected in Croatia and to identify differences between commercially produced eggs (cage, barn, and organic) and home-produced eggs (HPE).
Nina Bilandžić, Ines Varga, Jelena Kaurinović, Bruno Čalopek, Maja Đokić, Ivana Varenina, Božica Solomun Kolanović, Marija Sedak, Luka Cvetnić, Damir Pavliček, Elena Fattore   +10 more
doaj   +1 more source

De resíduo a insumo: a construção do caminho para uma química mais limpa através de um projeto de ensino From residue to input: building a road to clean chemistry through an educational project

Química Nova, 2008
The discussion among teachers, students, and technicians about the destination of residues from chemistry laboratories led to a research project whose results were incorporated into a course in its daily practices.
Regina Felisberto, Lucio Olimpio Vieira, Alessandra Couto, Roselena Schuh, Caroline Thiessen Albino, Daniela Batistela Libardi, Ana Cristina Borba da Cunha   +6 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Per- and Polyfluoroalkyl Substances in Fish: Global Occurrence, Bioaccumulation, Analytical Approaches, and Human Exposure Risks—A Review

Toxics
Per- and polyfluoroalkyl substances (PFAS) are highly stable and persistent environmental contaminants. Their exceptional chemical stability prevents natural breakdown, leading to global distribution and bioaccumulation in aquatic organisms.
Ines Varga, Nina Bilandžić, Jelena Kaurinović, Andrea Gross Bošković, Tomislav Klapec   +4 more
doaj   +1 more source

Pyrazolyl Methyls Prescribe the Electronic Properties of Iron(II) Tetra(pyrazolyl)lutidine Chloride Complexes [PDF]

, 2011
A series of iron(II) chloride complexes of pentadentate ligands related to α,α,α′,α′-tetra(pyrazolyl)-2,6-lutidine, pz4lut, has been prepared to evaluate whether pyrazolyl substitution has any systematic impact on the electronic properties of the ...
Bennett, Brian, Gardinier, James R., Grandjean, Fernande, Gwengo, Chengeto, Lindeman, Sergey, Long, Gary J., Makura, Vitales, Morin, Tyler James, Tatlock, Heidi M., Wanniarachchi, Sarath   +9 more
core   +2 more sources