Results 121 to 130 of about 1,104,642 (331)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Design of a Multiple Pseudorandom Number Generator Combined Chaotic System With RNS and Its Application to Secure Image Processing

open access: yesIEEE Access
This paper presents a novel approach to designing a multiple pseudorandom number generator (MPNG) through the integration of several key techniques. Specifically, the method leverages the chaotic dynamics of the 2D Tinkerbell system, a residue number ...
Chien-Chun Liu   +3 more
doaj   +1 more source

THE ANALYSIS OF MOTION DETECTION METHODS IN DIGITAL VIDEO SURVEILLANCE SYSTEMS

open access: yesСовременная наука и инновации, 2022
The article examines various methods of motion detection in the video stream. The modeling on the microcomputer Raspberry Pi 2 was carried out. The possibility of applying the residue number system for this problem was investigated, the scheme of the ...
Mikhail Grigorievich Babenko   +3 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

An Efficient Implementation of Montgomery Modular Multiplication Using a Minimally Redundant Residue Number System

open access: yesApplied Sciences
This paper presents an implementation of modular multiplication based on Montgomery’s scheme within the Residue Number System (RNS). The key innovation of the proposed approach lies in utilizing minimally redundant residue arithmetic, where the rank of a
Mikhail Selianinau   +1 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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