Results 61 to 70 of about 181,764 (294)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A distributed key establishment scheme for wireless mesh networks using identity-based cryptography [PDF]

open access: yes, 2010
In this paper, we propose a secure and efficient key establishment scheme designed with respect to the unique requirements of Wireless Mesh Networks. Our security model is based on Identity-based key establishment scheme without the utilization of a ...
Karaoglan, Duygu   +4 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

The Adolescent Brain: New Research and Its Implications for Young People Transitioning From Foster Care [PDF]

open access: yes, 2011
Outlines the developmental process adolescents undergo to become healthy, connected, and productive adults; implications for foster care youth, who often lack the supports needed to gain self-regulation, coping, and resiliency skills; and ...

core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Prężność osobowości i jej rola w procesach radzenia sobie ze stresem

open access: yesStudia Koszalińsko-Kołobrzeskie, 2016
This article is an attempt to show the sources and ways of understanding resiliency in the field of psychology. Firstly there are shown various approaches of understanding resiliency.
Adam Falewicz
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Exploring how parents of chronically ill children learn self-compassion

open access: yesDiscover Psychology
Objectives Parents of children with chronic illnesses face unique stressors that put them at risk for mental health disorders, such as anxiety, stress, and depression. In the U.S., 20% of families care for a child with a chronic health condition. Because
Phoebe Long Franco   +3 more
doaj   +1 more source

Complete mitochondrial genome of the yellow-lined snapper, Lutjanus rufolineatus Valenciennes, 1830 (Pisces, Lutjanidae), and notes on its phylogeny

open access: yesMitochondrial DNA. Part B. Resources
We report here the complete mitogenome of the yellow-lined snapper, Lutjanus rufolineatus (Valenciennes, 1830), from the Philippines. Primers designed from other Lutjanus species were used to amplify target regions via long-range PCR.
Carmela H. Lorico   +6 more
doaj   +1 more source

Resiliency and subjective health assessment. Moderating role of selected psychosocial variables

open access: yesHealth Psychology Report, 2015
Background Resiliency is defined as a relatively permanent personality trait, which may be assigned to the category of health resources. The aim of this study was to determine conditions in which resiliency poses a significant health resource ...
Michalina Sołtys, Agnieszka Woźniewicz
doaj   +1 more source

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