Results 71 to 80 of about 67,312 (295)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Economic stress indirectly predicts out-group prosocial behaviors during the Covid-19 pandemic differentially for young adults depending on ethnic group membership

Discover Psychology
The goal of the current study was to examine intervening culture and family related mechanisms in the links between pandemic-related economic stress and young adults’ ethnic out-group prosocial behaviors. Participants were 467 young adults (mean age = 22.
Gustavo Carlo, Alexandra N. Davis, Marixza Torres, Heidi Sanders, Lynda J. Cruz   +4 more
doaj   +1 more source

The Hydrogen Economy: Progress and Challenges to Future Growth

Hydrogen
The rally to mitigate growing carbon emissions and climate change necessitates decarbonization strategies, with hydrogen emerging as a key candidate option across multiple sectors. This review examines the current state of the hydrogen economy, including
Ifeanyi Oramulu, Vincent P. Paglioni
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Collective resilience

, 2021
info:eu-repo/semantics ...
Penic, Sandra, Drury, John, Bady, Zacharia   +2 more
openaire   +4 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The association between perceived organizational respect and fear of retribution

Heliyon
Objective: We examined the association between perceived organizational respect (POR) and fear of retribution (FoR) for expressing opinions among University of Utah Health Sciences campus employees, adjusting for demographic factors.
Gentry Carter, Ellen Morrow, Amy Locke, Megan E. Call, Jake Van Epps, José E. Rodríguez, Fares Qeadan   +6 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Exploring how parents of chronically ill children learn self-compassion

Discover Psychology
Objectives Parents of children with chronic illnesses face unique stressors that put them at risk for mental health disorders, such as anxiety, stress, and depression. In the U.S., 20% of families care for a child with a chronic health condition. Because
Phoebe Long Franco, Marissa C. Knox, Lauren E. Gulbas, Krista Gregory   +3 more
doaj   +1 more source