Results 21 to 30 of about 32,576 (217)
BMC Oral HealthBackground Given the limited evidence regarding the blending performance of single-shade resin composites with ceramic materials, this study aimed to investigate whether a single-shade resin composite can achieve superior color blending with hybrid ...
Jongchan Lee, Jinsoo Ahn, Sun-Young Kim
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Journal of Natural Fibers, 2023 This research is a study on the mechanical behavior of novel natural composites consisting of Aegle marmelos fruit resin and epoxy resin as matrix, basalt mat fibers, and Aegle fruit shell powder as reinforcement and fillers, respectively. The composites
Arul Jeya Kumar Arputham +3 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
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Applied Sciences, 2022 The design and preparation of hydrophobic, wear-resistant, and thermally conductive multifunctional composites is an important direction of scientific research and application.
Haichao Huang +6 more
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Crystals, 2022 Aim: Additional dry heat curing is a method that favorably influences the mechanical properties of an indirect resin composite restoration. Microflexural strength is a property currently applied for the evaluation of indirect resin composite restorations.
Marlon Zamalloa-Quintana +7 more
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
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Fracture Toughness of Resin Composites under Different Modes and Media: Review of Articles
Journal of Dental Biomaterial, 2015 This article aims to review various modes of fracture toughness of resin composites. Also, this study intends to review the papers on the fracture mode, namely “fractography”, under scanning electron microscopy finding fracture initiation site, and ...
Fani M, Farmani S, Bagheri R
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source