Results 41 to 50 of about 73,081 (288)

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Separation and Purification of Two Saponins from Paris polyphylla var. yunnanensis by a Macroporous Resin

open access: yesMolecules, 2022
An effective method for separating and purifying critical saponins (polyphyllin II and polyphyllin VII) from a Paris polyphylla var. yunnanensis extract was developed in this study which was environmentally friendly and economical.
Xiaoya Zhang   +7 more
doaj   +1 more source

Application of palynological techniques for correlation of coal seams in the Lower Lignite Creek area, Nenana Coal Field [PDF]

open access: yes, 1980
This study concerns spores and pollen in the coals of the lower Lignite Creek area in the Nenana Coal Field, which is operated by Usibelli Mining Company.
McFarlane, R., Sanders, R., and Rao, P.D.
core  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

EXTRACTION AND SEPARATION OF SOME ACTIVE COMPOUNDS IN ERUCA SATIVA AND STIUDY IT'S BIOLOGICAL ACTIVITY [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2014
This study aimed to sperat and extract of some active compounds in Eruca sativa .It included identificaion and determination of active compounds their percentages in the leaves,stem and seeds,like(Tannine, Glycosides,Alkaloids,Saponins,Resins,Flavonoids ...
MOHAMMED HAMEED – AL MOHAMMDI   +1 more
doaj   +1 more source

Guidelines on sustainable forest management in drylands of Ethiopia [PDF]

open access: yes, 2019
About 80% of forests in Ethiopia are dry forest. For the last 20 years they have been subject to land use changes, and replaced by agricultural land and settlements.
Atmadja, Stibniati   +2 more
core  

Effect of periodic backwash in the submerged membrane adsorption hybrid system [PDF]

open access: yes, 2006
The submerged membrane adsorption hybrid system (SMAHS) is an attractive solution in treating wastewater; however it faces membrane fouling although to a less extent.
Ben Aim, Roger   +4 more
core   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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