Results 71 to 80 of about 4,348,911 (323)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Experimental kinetic study of transesterification of ethyl acetate with methanol catalyzed by gel and macroporous acidic ion exchange resins [PDF]

, 2012
The reaction kinetics of the liquid-phase transesterification of ethyl acetate with methanol have been investigated over a series of commercially available ion-exchange resins. Two morphology types of cross-linked polymer resins have been considered, i.e.
De Clercq, Jeriffa, Thybaut, Joris, Van de Steene, Evelien   +2 more
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

A genomic approach to characterization of the Citrus terpene synthase gene family

Genetics and Molecular Biology, 2007
Terpenes are a very large and structurally diverse group of secondary metabolites which are abundant in many essential oils, resins and floral scents. Additionally, some terpenes have roles as phytoalexins in plant-pathogen relationships, allelopathic ...
Marcelo Carnier Dornelas, Paulo Mazzafera   +1 more
doaj   +1 more source

Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow, Matthew Katz, Jonathan Rodgers, Mark Davis, Thomas Robertson, R. J. McKinlay Gardner, Pamela A. McCombe   +6 more
wiley   +1 more source

Synthesis and application of hypercrosslinked polymers with weak cation-exchange character for the selective extraction of basic pharmaceuticals from complex environmental water samples [PDF]

, 2010
The synthesis of high specific surface area sorbents (HXLPP-WCX) in the form of hypercrosslinked polymer microspheres with narrow particle size distributions, average particle diameters around 6 µm, and weak cation exchange (WCX) character, is described.
Borrull, F., Bratkowska, D., Cormack, P.A.G., Fontanals, N., Marcé, R.M., Sherrington, D.C.   +5 more
core   +1 more source

Dynamic Precipitation during High‐Pressure Torsion of a Magnesium–Manganese Alloy

Advanced Engineering Materials, EarlyView.
An ultrafine‐grained alloy is produced by high‐pressure torsion of solutionized Mg–1.35 wt% Mn. Precipitation of nanometer‐scale Mn particles during deformation provides pinning sites. This prevents the formation of a bimodal grain structure and results in a finer grain size than for pure Mg.
Julian M. Rosalie, Anton Hohenwarter
wiley   +1 more source

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

Advanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes, Moritz Bätcher, Andrea Deißenberger, Volkmar Stenzel, Andreas Hartwig   +4 more
wiley   +1 more source

Potential of 5% tamarind extract gel as an etching agent: tensile strength and scanning electron microscope (SEM) evaluation

Dental Journal, 2020
Background: Acid etching is a stage in obtaining bonds between composites and enamel. The application of acid to the enamel surface, however, can cause dissolution of hydroxyapatite and demineralisation of the enamel surface.
Erawati Wulandari, Faiqatin Cahya Ramadhani, Nadie Fatimatuzzahro   +2 more
doaj   +1 more source

In silico and in vitro anti-inflammatory study of phenolic compounds isolated from Eucalyptus maculata resin

Scientific Reports, 2023
Plant resins are rich in bioactive compounds with high medicinal values. However, the chemistry and anti-inflammatory activity of the resins produced by trees of the genus Eucalyptus were scarcely investigated.
Dalia E. Ali, Rania A. El Gedaily, Shahira M. Ezzat, Maged A. El Sawy, Meselhy R. Meselhy, Essam Abdel-Sattar   +5 more
doaj   +1 more source