FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang+14 more
wiley +1 more source
Tuning singlet oxygen generation with caged organic photosensitizers. [PDF]
Nestoros E+12 more
europepmc +1 more source
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang+16 more
wiley +1 more source
Ecodesign Enhancement of Polymeric Resins: Reinforcing with Synthetic and Natural Fibers Using Theory of Inventive Problem Solving-Algorithm of Inventive Problem Solving for Sustainable Composite Design. [PDF]
Dobrotă D+4 more
europepmc +1 more source
Advances in Microfluidic Cochlea‐On‐A‐Chip
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen+10 more
wiley +1 more source
Preparation and Application of Humidity-Adaptive Wooden Artifact Crack Consolidants Based on Lignin-Epoxy Acrylate. [PDF]
Huang Q, Wu W, Wang Y, Zha J.
europepmc +1 more source
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei+15 more
wiley +1 more source
Recent Development of Functional Bio-Based Epoxy Resins. [PDF]
Zhang Y, Liu X, Wan M, Zhu Y, Zhang K.
europepmc +1 more source
Nanotherapy for Neural Retinal Regeneration
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu+11 more
wiley +1 more source
Unusual Lignocellulosic Bioresins: Adhesives and Coatings for Metals and Glass. [PDF]
Pizzi A.
europepmc +1 more source