Results 191 to 200 of about 25,743 (308)

Unlocking the Continuous Flow Asymmetric Hydrogenation of Olefins Through the Development of a Non-Deactivating Immobilized Iridium Catalyst. [PDF]

Angew Chem Int Ed Engl
Faiges J, Zanda N, Llanes P, Pericàs MA, Pàmies O, Diéguez M.   +5 more
europepmc   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Evaluation and Formulation of Hybridized Biobased Precursors as Anticorrosive Surface Coatings. [PDF]

Biomacromolecules
Kinaci E, Salazar SA, Palmese GR, Stanzione JF.   +3 more
europepmc   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Removal of iodine from organic media using diethylene triamine-grafted vinylbenzyl chloride-divinylbenzene resin. [PDF]

RSC Adv
Masood A, Khaliq K, Khan A, Ahmed Shafiq M, Shehzadi S, Rafique I, Akhtar R, Omer S, Anjum MAR, Iqbal S, Saifullah M.   +10 more
europepmc   +1 more source

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

Advanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza, Sheila Dakhel Plaza, Samuele Cazzamalli, Andrea Ciamarone, Andrea Galbiati, Riccardo Stucchi, Frederik Peissert, Emanuele Puca, Dario Neri, Ettore Gilardoni   +9 more
wiley   +1 more source

Revisiting applications of itaconic acid-based polymers obtained by (poly)condensation chemistry.

Green Chem
Bragato N, Papadopoulos L, Pasquale A, Pérocheau Arnaud S, Hakkarainen M, Pellis A, Robert T.   +6 more
europepmc   +1 more source

Development of ArgTag for Scalable Solid-Phase Synthesis of Aggregating Peptides. [PDF]

ACS Chem Biol
Freiburghaus V, Jeandin A, Frankiewicz Ł, Yang J, Hartrampf N.   +4 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Materials and Techniques in Dentistry, Oral Surgery and Orthodontics (Second Edition). [PDF]

Materials (Basel)
Sfondrini MF, Scribante A.
europepmc   +1 more source