Ultra-rapid and high-titer biomanufacturing of trehalose 6-phosphate by an in vitro synthetic biology platform. [PDF]
Liu B +5 more
europepmc +1 more source
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng +14 more
wiley +1 more source
Development of a Long-term Migration Test Method for Plastic Food Utensils, Containers, and Packaging. [PDF]
Mizuguchi-Fukase C +6 more
europepmc +1 more source
All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao +8 more
wiley +1 more source
The Multi-Attribute Method (MAM), An Advanced LC-MS Approach for Protein A Resin Performance and Lifecycle Evaluation. [PDF]
Zhang J +4 more
europepmc +1 more source
Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng +12 more
wiley +1 more source
Hygrothermal Durability and Damage Evolution of Bio-Epoxy-Based Composites Reinforced with Different Fibre Types. [PDF]
Iftikhar A +8 more
europepmc +1 more source
A Ceramic Network for Hybrid Solid Electrolyte Lithium Metal Batteries
An in‐plane aligned Ta‐LLZO ceramic network exhibits superior performance compared to conventional fillers, including single ceramic fibers and particles. The tortuosity within the polymeric phase of hybrid solid electrolytes is identified as a key parameter governing lithium‐ion transport pathways and dendrite suppression.
Luca Weckelmann +10 more
wiley +1 more source
Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai +7 more
wiley +1 more source

