Results 231 to 240 of about 1,998,168 (383)
Exploring Adults' Experiences with Tirzepatide for Weight Loss: A Mixed-Methods Study. [PDF]
Healthcare (Basel)Adam S +5 more
europepmc +1 more source
Resistive Training and Molecular Regulators of Vascular-Metabolic Risk in Chronic Stroke
, 2016 Alice S. Ryan +3 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Mice lacking ghrelin receptors resist the development of diet-induced obesity.
Journal of Clinical Investigation, 2005 J. Zigman +14 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Stress decreases the ability to resist smoking and potentiates smoking intensity and reward
Journal of Psychopharmacology, 2011 S. McKee +6 more
semanticscholar +1 more source