Results 81 to 90 of about 1,385,401 (335)

Latch mechanism [PDF]

open access: yes, 1972
Rachet device transfers loads imposed on latch to support structure before latch springs resist loads, positively locks two pivoted structures on contact, and carries loads in all ...
Ulrich, G. W.
core   +1 more source

Design and fabrication of densely integrated silicon quantum dots using a VLSI compatible hydrogen silsesquioxane electron beam lithography process

open access: yes, 2012
Hydrogen silsesquioxane (HSQ) is a high resolution negative-tone electron beam resist allowing for direct transfer of nanostructures into silicon-on-insulator.
A.J. Ferguson   +21 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

MALDI-TOF lipidomics rapidly detects modification of 2-hydroxymyristate lipid A, a potential virulence trait in Enterobacter bugandensis

open access: yesMicrobiology Spectrum
Enterobacter cloacae complex (ECC) comprises numerous species that can be difficult to identify. Among these species, Enterobacter bugandensis is recognized as a threat in neonatal intensive care units due to its involvement in septic shock.
Rémy A. Bonnin   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Performance of disc diffusion and four commercially available MIC tests to determine mecillinam susceptibility on carbapenemase-producing Enterobacterales

open access: yesJournal of Clinical Microbiology
Urinary tract infections (UTIs) are predominantly caused by Enterobacterales, and escalating resistance poses significant challenges due to carbapenemase production, which can compromise the efficacy of last-resort antibiotics.
Sacha Milleville   +7 more
doaj   +1 more source

Enhancement of superconductivity in NbN nanowires by negative electron-beam lithography with positive resist

open access: yes, 2017
We performed comparative experimental investigation of superconducting NbN nanowires which were prepared by means of positive-and negative electron-beam lithography with the same positive tone Poly-methyl-methacrylate (PMMA) resist.
A. Kuzmin   +11 more
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Modal analysis and dynamic stresses for acoustically excited shuttle insulation tiles [PDF]

open access: yes
Improvements and extensions to the RESIST computer program developed for determining the normalized modal stress response of shuttle insulation tiles are described.
Ogilvie, P. L., Ojalvo, I. U.
core   +1 more source

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