Results 101 to 110 of about 11,899,956 (387)

Identification and mapping of the novel apple scab resistance gene Vd3 [PDF]

, 2009
Apple scab, caused by the fungal pathogen Venturia inaequalis, is one of the most devastating diseases for the apple growing in temperate zones with humid springs and summers.
Groenwold, R., Henken, G., Joshi, S.G., Kaauwen, M.P.W., van, Noordijk, Y., Schouten, H.J., Soriano Soriano, J.M., Weg, W.E., van de   +7 more
core   +2 more sources

Resistance in Vancomycin-Resistant Enterococci

Infectious Disease Clinics of North America, 2020
Serious infections owing to vancomycin-resistant enterococci have historically proven to be difficult clinical cases, requiring combination therapy and management of treatment-related toxicity. Despite the introduction of new antibiotics with activity against vancomycin-resistant enterococci to the therapeutic armamentarium, significant challenges ...
William R, Miller, Barbara E, Murray, Louis B, Rice, Cesar A, Arias   +3 more
openaire   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Investigating the relationship between Pfkelch13 mutations and response to artemisinin-based treatment for uncomplicated falciparum malaria: a protocol for a systematic review and individual patient data meta-analysis

BMJ Open
Introduction Artemisinin-based combination therapies (ACTs) remain the WHO-recommended treatment for uncomplicated Plasmodium falciparum malaria. However, the emergence and spread of artemisinin resistance (ART-R) threatens ACT efficacy.
Prabin Dahal, Philippe Guerin, Farhad Shokraneh, James A Watson, Karen I Barnes, Aboubakar Soma, Stephanie van Wyk, Chistevy Vouvoungui, Dhol S Ayuen   +8 more
doaj   +1 more source

Modified genome comparison method: a new approach for identification of specific targets in molecular diagnostic tests using Mycobacterium tuberculosis complex as an example

BMC Infectious Diseases, 2018
Background The first step of designing any genome-based molecular diagnostic test is to find a specific target sequence. The modified genome comparison method is one of the easiest and most comprehensive ways to achieve this goal. In this study, we aimed
Alireza Neshani, Reza Kamali Kakhki, Mojtaba Sankian, Hosna Zare, Amin Hooshyar Chichaklu, Mahsa Sayyadi, Kiarash Ghazvini   +6 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Diagnosis and Management of Dengue Fever in a Nonendemic Country: Lessons From an Acute Febrile Illness in Iran During the COVID-19 Outbreak

Case Reports in Infectious Diseases
Dengue fever is a tropical arboviral disease that presents with a broad spectrum of clinical manifestations and can occasionally emerge in nonendemic regions due to factors such as international travel.
Kimia Mozahheb Yousefi, Solaleh Aminian, Masoud Ebrahimi, Sara Minaeian, Azadeh Laali   +4 more
doaj   +1 more source

Detection of Multi-drug Resistant \u3cem\u3eEscherichia coli\u3c/em\u3e in the Urban Waterways of Milwaukee, WI [PDF]

, 2015
Urban waterways represent a natural reservoir of antibiotic resistance which may provide a source of transferable genetic elements to human commensal bacteria and pathogens. The objective of this study was to evaluate antibiotic resistance of Escherichia
Ahuja, Neha H., DeNies, Maxwell S., Hristova, Krassimira R., Kappell, Anthony D., Ledeboer, Nathan A., Newton, Ryan J.   +5 more
core   +1 more source

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

The Lancet, 2022
Christopher J L Kevin Shunji Fablina Lucien Gisela Authia Chie Murray Ikuta Sharara Swetschinski Robles Aguilar G, Christopher J. L. Murray, K. Ikuta, Fablina Sharara, Lucien R. Swetschinski, Gisela Robles Aguilar, Authia Gray, Chieh Han, C. Bisignano, P. Rao, Eve E. Wool, Sarah C Johnson, A. Browne, M. Chipeta, Frederick Fell, Sean Hackett, G. Haines-Woodhouse, Bahar H. Kashef Hamadani, E. Kumaran, Barney McManigal, Sureeruk Achalapong, R. Agarwal, S. Akech, Samuel B. Albertson, J. Amuasi, J. Andrews, A. Aravkin, Elizabeth A Ashley, F. Babin, F. Bailey, S. Baker, B. Basnyat, A. Bekker, Rose G. Bender, J. Berkley, Adhisivam Bethou, J. Bielicki, S. Boonkasidecha, James Bukosia, C. Carvalheiro, C. Castañeda-Orjuela, Vilada Chansamouth, S. Chaurasia, S. Chiurchiù, F. Chowdhury, Rafai Clotaire Donatien, A. Cook, B. Cooper, T. Cressey, E. Criollo-Mora, M. Cunningham, Saffiatou Darboe, N. Day, M. De Luca, K. Dokova, A. Dramowski, S. Dunachie, Thuy Duong Bich, T. Eckmanns, D. Eibach, A. Emami, N. Feasey, Natasha Fisher-Pearson, K. Forrest, Coralith García, D. Garrett, P. Gastmeier, A. Z. Giref, R. Greer, Vikas Gupta, S. Haller, A. Haselbeck, Simon Iain Hay, M. Holm, S. Hopkins, Y. Hsia, K. Iregbu, J. Jacobs, D. Jarovsky, F. Javanmardi, A. Jenney, M. Khorana, S. Khusuwan, N. Kissoon, Elsa Kobeissi, T. Kostyanev, F. Krapp, R. Krumkamp, Ajay Kumar, H. Kyu, C. Lim, K. Lim, D. Limmathurotsakul, M. Loftus, Miles Lunn, Jianing Ma, A. Manoharan, F. Marks, J. May, M. Mayxay, N. Mturi, Tatiana Múnera-Huertas, P. Musicha, Lilian A Musila, M. Mussi-Pinhata, R. Naidu, Tomoka Nakamura, R. Nanavati, S. Nangia, P. Newton, C. Ngoun, Amanda Novotney, D. Nwakanma, C. Obiero, T. Ochoa, A. Olivas-Martínez, P. Olliaro, Edna Ooko, E. Ortiz-Brizuela, P. Ounchanum, G. Pak, J. Paredes, A. Peleg, Carlo Perrone, T. Phe, Koukeo Phommasone, N. Plakkal, A. Ponce-de-León, Mathieu Raad, T. Ramdin, S. Rattanavong, A. Riddell, T. Roberts, J. Robotham, A. Roca, V. Rosenthal, K. Rudd, N. Russell, H. Sader, Weerawut Saengchan, Jesse Schnall, J. Scott, Samroeng Seekaew, M. Sharland, M. Shivamallappa, J. Sifuentes-Osornio, A. Simpson, N. Steenkeste, A. Stewardson, T. Stoeva, Nidanuch Tasak, Areerat Thaiprakong, G. Thwaites, C. Tigoi, C. Turner, P. Turner, H. R. van Doorn, S. Velaphi, Avina Vongpradith, M. Vongsouvath, Huong X. Vu, T. Walsh, J. Walson, S. Waner, T. Wangrangsimakul, P. Wannapinij, T. Wozniak, Tracey E M W Young Sharma, Kalvin C. Yu, Peng Zheng, B. Sartorius, Alan D. Lopez, A. Stergachis, C. Moore, C. Dolecek, M. Naghavi   +175 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source