Results 11 to 20 of about 3,014,748 (294)

Resistance-resistant antibiotics [PDF]

open access: yesTrends in Pharmacological Sciences, 2014
New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric Oldfield, Xinxin Feng
openaire   +3 more sources

Resistance or pseudo-resistance?

open access: yesEuropean Psychiatry, 2022
IntroductionTreatment-Resistant Depression continues to represent a great challenge for clinicians.ObjectivesWe investigated patients with history of resistance, assessing prognostic factors, response to treatments, and remission over time.MethodsWe recruited 202 unipolar and bipolar depressed inpatients.
R. Zanardi   +4 more
openaire   +2 more sources

Random 2D nanowire networks: Finite-size effect and the effect of busbar/nanowire contact resistance on their electrical conductivity [PDF]

open access: yesJournal of Applied Physics, Vol.132, Iss. 12, 125105 (2022), 2022
We have studied the resistance of two-dimensional random percolating networks of zero-width metallic nanowires (rings or sticks). We toke into account the nanowire resistance per unit length, the junction (nanowire/nanowire contact) resistance, and the busbar/nanowire contact resistance.
arxiv   +1 more source

Resisting Potato Cyst Nematodes With Resistance [PDF]

open access: yesFrontiers in Plant Science, 2021
Potato cyst nematodes (PCN) are economically important pests with a worldwide distribution in all temperate regions where potatoes are grown. Because above ground symptoms are non-specific, and detection of cysts in the soil is determined by the intensity of sampling, infestations are frequently spread before they are recognised.
Ulrike Gartner   +14 more
openaire   +6 more sources

Microbial resistance or team resistance? [PDF]

open access: yesBMC Proceedings, 2011
Introduction / objectives Errors in the process of drug therapy has been an issue for the change in the epidemiological profile of microorganisms, causing antibiotic resistance. Whereas full-time care of the nursing staff in patient care, was aimed to analyze the errors which undoubtedly may be preventable with measures of interventions and reflect on ...
Camila Megumi Naka Shimura, J Da Silva
openaire   +2 more sources

Resistance to “Castration-Resistant” [PDF]

open access: yesThe Oncologist, 2014
The author challenges the use of the phrase “castration resistance,” which is widely used in the literature and also appears in a recent article by Merseburger et al.
openaire   +3 more sources

Resisting the Resistance: Resisting Copyright and Promoting Alternatives

open access: yesSSRN Electronic Journal, 2017
This article discusses the resistance to the Digital Revolution and the emergence of a social movement “resisting the resistance.” Mass empowerment has political implications that may provoke reactionary counteractions. Ultimately—as I have discussed elsewhere—resistance to the Digital Revolution can be seen as a response to Baudrillard’s call to a ...
Giancarlo Frosio, Giancarlo Frosio
openaire   +6 more sources

Imaginative Resistance and Empathic Resistance [PDF]

open access: yesTopoi, 2019
In the past few decades, a growing number of philosophers have tried to explain the phenomenon of imaginative resistance (IR), or why readers often resist the invitation of authors to imagine morally deviant fictional scenarios. In this paper, I critically assess a recent proposal to explain IR in terms of a failure of empathy, and present a novel ...
Thomas Szanto, Thomas Szanto
openaire   +4 more sources

Resistance in Vancomycin-Resistant Enterococci

open access: yesInfectious Disease Clinics of North America, 2020
Serious infections owing to vancomycin-resistant enterococci have historically proven to be difficult clinical cases, requiring combination therapy and management of treatment-related toxicity. Despite the introduction of new antibiotics with activity against vancomycin-resistant enterococci to the therapeutic armamentarium, significant challenges ...
Barbara E. Murray   +3 more
openaire   +4 more sources

Resisting Bacterial Drug Resistance [PDF]

open access: yesChemistry & Biology, 2003
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire   +3 more sources

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