Results 11 to 20 of about 5,098,765 (316)
Resistance-resistant antibiotics [PDF]
New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric, Oldfield, Xinxin, Feng
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Targeted therapies, immunotherapies, and improved chemotherapies are being developed to reduce the suffering and mortality that come from human cancer. Although these approaches, and in particular combinations of them, are expected to succeed eventually to a large degree, they all suffer one obstacle: Populations of replicating cells move away ...
Ivana Bozic, Martin A. Nowak
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Resistance to “Castration-Resistant” [PDF]
The author challenges the use of the phrase “castration resistance,” which is widely used in the literature and also appears in a recent article by Merseburger et al.
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Manual wheelchair's turning resistance: swivelling resistance parameters of front and rear wheels on different surfaces [PDF]
Purpose: Daily locomotion with a manual wheelchair includes curvilinear movements. However, little is known about the resisting forces in play during turning manoeuvres where the wheels are generally both rolling and swivelling.
BASCOU, Joseph +3 more
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Antimicrobial drug use and resistance in Europe [PDF]
Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000–2005 and explores whether the notion that ...
Grundmann, Hajo +8 more
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Background: A collection of human-epidemiologically unrelated S. enterica strains collected over a 3-year period (2016 to 2018) in Italy by the national surveillance Enter-Net Italia was analysed.
Claudia Lucarelli +9 more
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Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance [PDF]
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
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Resisting Potato Cyst Nematodes With Resistance [PDF]
Potato cyst nematodes (PCN) are economically important pests with a worldwide distribution in all temperate regions where potatoes are grown. Because above ground symptoms are non-specific, and detection of cysts in the soil is determined by the intensity of sampling, infestations are frequently spread before they are recognised.
Ulrike Gartner +14 more
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Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study. [PDF]
BACKGROUND: Increasing pyrethroid resistance has been an undesirable correlate of the rapid increase in coverage of insecticide-treated nets (ITNs) since 2000.
Implications of Insecticide Resistance Consortium
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Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe +2 more
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