Results 11 to 20 of about 5,098,765 (316)

Resistance-resistant antibiotics [PDF]

open access: yesTrends in Pharmacological Sciences, 2014
New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric, Oldfield, Xinxin, Feng
openaire   +2 more sources

Resisting Resistance [PDF]

open access: yesAnnual Review of Cancer Biology, 2017
Targeted therapies, immunotherapies, and improved chemotherapies are being developed to reduce the suffering and mortality that come from human cancer. Although these approaches, and in particular combinations of them, are expected to succeed eventually to a large degree, they all suffer one obstacle: Populations of replicating cells move away ...
Ivana Bozic, Martin A. Nowak
openaire   +1 more source

Resistance to “Castration-Resistant” [PDF]

open access: yesThe Oncologist, 2014
The author challenges the use of the phrase “castration resistance,” which is widely used in the literature and also appears in a recent article by Merseburger et al.
openaire   +2 more sources

Manual wheelchair's turning resistance: swivelling resistance parameters of front and rear wheels on different surfaces [PDF]

open access: yes, 2019
Purpose: Daily locomotion with a manual wheelchair includes curvilinear movements. However, little is known about the resisting forces in play during turning manoeuvres where the wheels are generally both rolling and swivelling.
BASCOU, Joseph   +3 more
core   +1 more source

Antimicrobial drug use and resistance in Europe [PDF]

open access: yes, 2008
Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000–2005 and explores whether the notion that ...
Grundmann, Hajo   +8 more
core   +1 more source

Colistin Resistance Mechanisms in Human Salmonella enterica Strains Isolated by the National Surveillance Enter-Net Italia (2016–2018)

open access: yes, 2022
Background: A collection of human-epidemiologically unrelated S. enterica strains collected over a 3-year period (2016 to 2018) in Italy by the national surveillance Enter-Net Italia was analysed.
Claudia Lucarelli   +9 more
core   +1 more source

Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance [PDF]

open access: yes, 2005
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
core   +1 more source

Resisting Potato Cyst Nematodes With Resistance [PDF]

open access: yesFrontiers in Plant Science, 2021
Potato cyst nematodes (PCN) are economically important pests with a worldwide distribution in all temperate regions where potatoes are grown. Because above ground symptoms are non-specific, and detection of cysts in the soil is determined by the intensity of sampling, infestations are frequently spread before they are recognised.
Ulrike Gartner   +14 more
openaire   +5 more sources

Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study. [PDF]

open access: yes, 2018
BACKGROUND: Increasing pyrethroid resistance has been an undesirable correlate of the rapid increase in coverage of insecticide-treated nets (ITNs) since 2000.
Implications of Insecticide Resistance Consortium
core   +1 more source

Supranational surveillance of antimicrobial resistance: The legacy of the last decade and proposals for the future

open access: yes, 2010
Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe   +2 more
core   +1 more source

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