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Resistance-resistant antibiotics [PDF]
New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric, Oldfield, Xinxin, Feng
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Resistance to “Castration-Resistant” [PDF]
The author challenges the use of the phrase “castration resistance,” which is widely used in the literature and also appears in a recent article by Merseburger et al.
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Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
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The spread of the gene encoding the NDM-type carbapenemase, bla NDM, poses a serious threat to clinical practice and public health. This gene is usually carried by transferable plasmids, which facilitates its rapid spread among various species of ...
Hui Zuo +5 more
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Background The prevalence of Acinetobacter baumannii in nosocomial infections and its remarkable ability to develop antimicrobial resistance have been a critical issue in hospital settings.
Made Rai Dwitya Wiradiputra +4 more
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Background Weanling pigs, with immature immune system and physiological function, usually experience post-weaning diarrhea. This study determined the effects of dietary Clostridium butyricum supplementation on growth performance, diarrhea, and immunity ...
Ling Chen +12 more
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Bacteria possess elaborate systems to manage reactive oxygen and nitrogen species (ROS) arising from exposure to the mammalian immune system and environmental stresses.
Wei Lin Lee +10 more
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Background Plant respiratory burst oxidase homolog (Rboh) gene family produces reactive oxygen species (ROS), and it plays key roles in plant–microbe interaction.
Fulang Wu +5 more
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Targeted therapies, immunotherapies, and improved chemotherapies are being developed to reduce the suffering and mortality that come from human cancer. Although these approaches, and in particular combinations of them, are expected to succeed eventually to a large degree, they all suffer one obstacle: Populations of replicating cells move away ...
Ivana Bozic, Martin A. Nowak
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In Germany, the first six-rowed waxy winter barley cultivar (cv.) `Waxyma` was registered in 2008. Besides changes in starch composition, waxy barley is rich in ß-glucans offering new applications in the food industry as ß-glucans reduce the blood ...
Gisela Jansen +3 more
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