Results 201 to 210 of about 5,098,765 (316)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Clinically relevant mutations contributing to drug resistance in Mycobacterium tuberculosis

, 2017
Juanelle Du Plessis
openalex   +1 more source

Genotype Versus Phenotype in Pandrug-Resistant <i>Pseudomonas aeruginosa</i>: Key Considerations for Interpretation. [PDF]

Clin Med Insights Case Rep
Suvvari TK, Kandi V, Kocharlakota SV.
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

eLife Assessment: Magnesium modulates phospholipid metabolism to promote bacterial phenotypic resistance to antibiotics

Musa Mohammed Ali
openalex   +1 more source

Elevated alanine aminotransferase activity is not associated with dyslipidemias, but related to insulin resistance and higher disease grades in non-diabetic non-alcoholic fatty liver disease

, 2012
Mohammad Ebrahim Ghamarchehreh, Mohsen Amini, Hossein Khedmat, Seyed Moayed Alavian, Fatemeh Daraei, Reza Mohtashami, Reza Hadi, Bent-Al-Hoda Beyram, Saeed Taheri   +8 more
openalex   +2 more sources

Limitations of Global Surveillance for Neisseria gonorrhoeae Antimicrobial Resistance. [PDF]

Emerg Infect Dis
van Hal SJ, Fifer H, Lahra MM.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source