Results 221 to 230 of about 6,548,311 (348)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Local therapy overcomes primary resistance to target-immunotherapy combination in unresectable hepatocellular carcinoma. [PDF]

open access: yesCancer Immunol Immunother
Chen X   +12 more
europepmc   +1 more source

TLR4 links innate immunity and fatty acid-induced insulin resistance.

open access: yesJournal of Clinical Investigation, 2006
Hang Shi   +5 more
semanticscholar   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

HIV Dolutegravir resistance and multiclass failure in Mozambique: findings from a real-world cohort. [PDF]

open access: yesBMC Infect Dis
Ciccacci F   +9 more
europepmc   +1 more source

A view on drug resistance in cancer

open access: yesNature, 2019
N. Vasan, J. Baselga, D. Hyman
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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