Results 31 to 40 of about 449,331 (264)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Genome-wide identification and analysis of monocot-specific chimeric jacalins (MCJ) genes in Maize (Zea mays L.)

BMC Plant Biology
Background The monocot chimeric jacalins (MCJ) proteins, which contain a jacalin-related lectin (JRL) domain and a dirigent domain (DIR), are specific to Poaceae.
Hailong Jiang, Jiajian Peng, Qian Li, Siqian Geng, Hualei Zhang, Yuting Shu, Rui Wang, Bin Zhang, Changsheng Li, Xiaoli Xiang   +9 more
doaj   +1 more source

Whole-Genome Duplication and Purifying Selection Contributes to the Functional Redundancy of Auxin Response Factor (ARF) Genes in Foxtail Millet (Setaria italica L.)

International Journal of Genomics, 2021
Auxin response factors (ARFs) play crucial roles in auxin-mediated response, whereas molecular genetics of ARF genes was seldom investigated in Setaria italica, an important crop and C4 model plant. In the present study, genome-wide evolutionary analysis
You Chen, Bin Liu, Yujun Zhao, Wenzhe Yu, Weina Si   +4 more
doaj   +1 more source

9-cis-epoxycarotenoid dioxygenase 1 confers heat stress tolerance in rice seedling plants

Frontiers in Plant Science, 2022
High temperature is one of the main constraints affecting plant growth and development. It has been reported that abscisic acid (ABA) synthesis gene 9-cis-epoxycarotenoid dioxygenase (NCED) positively regulates plant resistance to salt, cold, and drought
Yijin Zhang, Yijin Zhang, Xiong Liu, Xiong Liu, Rui Su, Rui Su, Yunhua Xiao, Yunhua Xiao, Huabing Deng, Huabing Deng, Xuedan Lu, Xuedan Lu, Feng Wang, Feng Wang, Guihua Chen, Wenbang Tang, Wenbang Tang, Wenbang Tang, Wenbang Tang, Guilian Zhang, Guilian Zhang   +20 more
doaj   +1 more source

Norwegian dairy farmer's preferences for breeding goal traits and associations with herd and farm characteristics [PDF]

, 2019
The aims of this study were to investigate variation and clustering in breeding goal trait preferences among Norwegian dairy farmers and to identify factors with a systematic influence on their preferences. An internet-based questionnaire was sent out to
Eriksson, S., Grøva, Lise, Kargo, M., Skjerve, T., Slagboom, Margot, Sørheim, Kristin, Wallenbeck, Anna   +6 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Rice cellulose synthase-like protein OsCSLD4 coordinates the trade-off between plant growth and defense

Frontiers in Plant Science, 2022
Plant cell wall is a complex and changeable structure, which is very important for plant growth and development. It is clear that cell wall polysaccharide synthases have critical functions in rice growth and abiotic stress, yet their role in plant ...
Xiong Liu, Xiong Liu, Zhongliang Yin, Zhongliang Yin, Yubo Wang, Yubo Wang, Sai Cao, Sai Cao, Wei Yao, Jinling Liu, Xuedan Lu, Xuedan Lu, Feng Wang, Feng Wang, Guilian Zhang, Guilian Zhang, Yunhua Xiao, Yunhua Xiao, Wenbang Tang, Wenbang Tang, Wenbang Tang, Wenbang Tang, Huabing Deng, Huabing Deng   +23 more
doaj   +1 more source

Resistance Breeding in Apple at Dresden-Pillnitz [PDF]

, 2008
Resistance breeding in apple has a long tradition at the Institute of Fruit Breeding now Julius Kuehn-institute in Dresden-Pillnitz. The breeding was aimed at the production of multiple resistance cultivars to allow a more sustainable and environmentally
Dunemann, F., Flachowsky, H., Hanke, M.-V., Hoefer, M., Király, I., Peil, A., Richter, K.   +6 more
core  

Exploiting Erianthus diversity to enhance sugarcane cultivars.[W1024] [PDF]

, 2020
Introgression of Erianthus arundinaceus into the SRA sugarcane-breeding program has been a goal for researchers for many years. The Erianthus genome was finally accessible to sugarcane breeders with the identification in 2005 of the first Saccharum ...
Aitken, Karen S., Atkin, Felicity, Garsmeur, Olivier, Piperidis, George, Piperidis, Nathalie, Tom, Chris   +5 more
core