Results 171 to 180 of about 3,355,637 (249)

Krüppel‐like factor 4 transcription factor in blood–brain barrier endothelial cells: A potential role in Alzheimer's disease

open access: yesAnimal Models and Experimental Medicine, EarlyView.
KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei   +4 more
wiley   +1 more source

Evolution‐Guided Discovery of Antimycobacterial Triculamin‐Like Lasso Peptides

open access: yesAngewandte Chemie, EarlyView.
The hypothesized convergent biosynthesis of triculamin‐like lasso peptides from different biosynthetic gene cluster (BGC) types represented across multiple bacterial phyla. The elucidation of the triculamin non‐canonical BGC and resistance mechanism by heterologous expression in Streptomyces albus and in vitro acetylation with resistance conveying ...
Aske Merrild   +3 more
wiley   +2 more sources

Suppressing selection for antibiotic resistance in the environment: A transparent, ecology-based approach to predicted no-effect concentrations

open access: green
David Kneis   +9 more
openalex   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He   +11 more
wiley   +1 more source

In Situ High Selectivity Contact‐Electroreduction of CO2 to Methanol Using an Imine‐Mediated Metal‐Free Vitrimer Catalyst

open access: yesAngewandte Chemie, EarlyView.
A vitrimer catalyst with C═N bond enables efficient CO2 reduction via contact‐electrocatalysis, driven by water droplet‐induced charges. Imine groups stabilize CO2 adsorption, enrich electrons, and mediate electron transfer, achieving >90% methanol selectivity.
Nannan Wang   +6 more
wiley   +2 more sources

Editorial: Fighting antimicrobial resistance in developing countries: innovative approaches and challenges. [PDF]

open access: yesFront Cell Infect Microbiol
Katipoglu-Yazan T   +3 more
europepmc   +1 more source

Towards Polymer Composite‐Based Transient Electronic Systems

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko   +5 more
wiley   +1 more source

Decoding the Chemical Language of Ribosomally Synthesized and Post‐Translationally Modified Peptides from the Untapped Archaea Domain

open access: yesAngewandte Chemie, EarlyView.
Secondary metabolites (SMs) are essential across all life domains, yet those originating from the Archaea domain remain poorly understood. Here, the systematic genome mining and the pioneering heterologous expression of archaeal SMs have revealed the chemical landscape of archaeal lanthipeptides, showing both canonical and non‐canonical forms.
Zhi‐Man Song   +13 more
wiley   +2 more sources

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