Results 201 to 210 of about 3,863,183 (351)

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Internationalconference honors pioneers in quantitative microbial physiology and ecology. [PDF]

Natl Sci Rev
Lu Q, Li X.
europepmc   +1 more source

Inhibition of RNase to Attenuate Fungal‐Manipulated Rhizosphere Microbiome and Diseases

Advanced Science, EarlyView.
Fusarium graminearum uses its virulence effector Fg12, a fungal RNase, to manipulate the host rhizosphere microbiome and promote infection. Guanosine monophosphate (GMP) blocks Fg12's RNase activity. This reveals a key pathogen‐microbiota interaction mechanism and proposes GMP as a targeted strategy to disarm this core fungal effector, offering a ...
Bo Yang, Sen Yang, Xiaomi Wang, Yuanwei Zhang, Yao Zhao, Menghuan Tao, Jinyi Zhu, Wanxin Zhang, Yansu Wang, Kaixuan Duan, Yan Wang, Wenwu Ye, Zhenfei Guo, Yuanchao Wang   +13 more
wiley   +1 more source

Correction: Microbial exchange at the wildlife-livestock interface: insights into microbial composition, antimicrobial resistance and virulence factor gene dynamics in grassland ecosystems. [PDF]

Anim Microbiome
Kauer L, Sapountzis P, Imholt C, Berens C, Kuehn R.   +4 more
europepmc   +1 more source

Toward a Species Search Engine: KISSE Offers a Rigorous Statistical Framework for Bone Collagen Tandem Mass Spectrometry Data

Advanced Science, EarlyView.
The Species Search Engine (KISSE) is a novel statistical approach for identifying species from collagen peptides, using a curated library of sequences and their relative abundances derived from shotgun proteomics. Abstract DNA and bone collagen are two key sources of resilient molecular markers used to identify species from their remains.
Hassan Gharibi, Amir Ata Saei, Alexey L. Chernobrovkin, Susanna L. Lundstrom, Hezheng Lyu, Zhaowei Meng, Akos Vegvari, Massimilliano Gaetani, Roman A. Zubarev   +8 more
wiley   +1 more source

Opposing Effects of Plant Invasion on the Stability of Aboveground and Belowground Net Primary Productivity in an Alpine Grassland. [PDF]

Ecol Evol
Ren QJ, Li KH, Wang HF, Liu YY, Gong YM.
europepmc   +1 more source

Polyadenylation Complex CFII Recognizes Downstream Cis‐element for Pre‐mRNA Polyadenylation Through Interaction with an RNA‐Binding Protein in Arabidopsis

Advanced Science, EarlyView.
This study investigates the cis‐element in pre‐mRNA recognized by the polyadenylation CFII complex. It elucidates how the CFII complex recognizes the consensus cis‐element downstream of the poly(A) site for pre‐mRNA alternative polyadenylation. This comprehensive research provides novel insights into the interaction between 3′ end processing complexes ...
Ying Cao, Ying Guo, Zhibo Yu, Huajian Nie, Jing Yang, Dingfu Qiu, Qiyu Li, Xu Xin, Chang Cheng, Yan Li, Xudong Shang, Yuling Jiao, Qingshun Quinn Li, Ligeng Ma   +13 more
wiley   +1 more source

Belowground Communities in Lowlands Are Less Stable to Heat Extremes Across Seasons. [PDF]

Ecol Lett
Martínez-De León G, Formenti L, Salamon JA, Thakur MP.   +3 more
europepmc   +1 more source

Storage Potential of Soil Functional Carbon Fractions in the World's Largest Plantations

Advanced Science, EarlyView.
Climate warming and drying increase the loss of mineral‐associated and particulate organic carbon during the conversion of natural forests to plantations. Based on a survey of the world's largest plantations, the study quantifies the soil carbon deficit in plantations and assesses benchmarks and targets for functional soil organic carbon, highlighting ...
Siyu Ren, Hui Wang, Tao Zhou, Chuankuan Wang, Zhenghu Zhou, Shirong Liu   +5 more
wiley   +1 more source

Impact of genotypes, environmental stresses, and genotype by environment interactions on growth and yield of quinoa at flowering stage. [PDF]

PLoS One
Loc Nguyen V, Do TH, Phan THN, Nguyen VL, Chu DH, Bertero D, Curti N, Ta VT, McKeown PC, Spillane C.   +9 more
europepmc   +1 more source