Results 291 to 300 of about 494,662 (360)

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

open access: yesAdvanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park   +5 more
wiley   +1 more source

An Inflammation‐Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti‐TNF‐α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
Ulcerative colitis therapy requires precise drug targeting. This study engineers a probiotic E. coli Nissle 1917 to surface‐display ANXA5, enabling specific binding to phosphatidylserine (PS) exposed on inflamed colonic epithelium for enhanced targeting and colonization.
Siqi Hua   +6 more
wiley   +1 more source

Ecology and epidemiology of multidrug-resistant <i>Salmonella</i> in synanthropic small mammals in Bangladesh. [PDF]

open access: yesOne Health
Rumi MA   +10 more
europepmc   +1 more source

Vacancy Engineered Zero‐Valent Iron Steer Hydrogen Spillover toward Per‐ and Polychlorinated Organics Rapid Complete Dechlorination

open access: yesAdvanced Science, EarlyView.
Zero‐valent iron with a vacancy‐rich carbon shell and lattice Cu doping in Fe0 cores generates a dechlorination mechanism combining enhanced electron transfer and modulated H* spillover, which significantly lowers the energy barrier for dechlorinating low‐chlorinated intermediates, accelerates C─Cl bond dissociation, and then delivers breakthrough ...
Zimin Yan   +7 more
wiley   +1 more source

An Engineered Probiotic Consortium Based on Quorum‐Sensing for Colorectal Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This work develops an engineered probiotic consortium sensing pH, hypoxia, and lactate in the tumor microenvironment. It releases a lactate‐depleting enzyme (LdhA) and a PD‐L1 nanobody. In humanized mouse models (MC38 and HT‐29 tumors), it achieves durable oscillations, suppresses tumors, activates CD8+, CD4+, IFN‐γ+ T cells, and reduces Foxp3 ...
Yufei Guo   +11 more
wiley   +1 more source

Electronic‐Structure‐Guided Screening of Piperazine Derivatives: Achieving Efficient CO2 Capture with High Cyclic Capacity and Low Energy Consumption

open access: yesAdvanced Science, EarlyView.
A density functional theory (DFT)‐based framework is proposed to predict CO2 capture performance of piperazine derivatives. 2,6‐dimethylpiperazine (26DMPZ) is identified as a promising candidate: CO2‐induced precipitation in water eliminates the need for organic solvents; the low‐solubility, unstable dicarbamate enhances CO2 capture efficiency and ...
Feng Xie   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy