Results 111 to 120 of about 3,385,258 (303)

Resistance and aerobic training increases genome-wide DNA methylation in women with polycystic ovary syndrome

Epigenetics
Physical activity is a first-line treatment for polycystic ovary syndrome (PCOS). Resistance or aerobic exercise improves metabolic complications, reproductive outcomes, and quality of life in PCOS.
Cristiana Libardi Miranda Furtado, Megan Hansen, Gislaine Satyko Kogure, Victor Barbosa Ribeiro, Nathanael Taylor, Murilo Racy Soares, Rui Alberto Ferriani, Kenneth Ivan Aston, Timothy Jenkins, Rosana Maria dos Reis   +9 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Network meta-analysis of the intervention effects of different exercise measures on Sarcopenia in cancer patients

BMC Public Health
Purpose This study aims to investigate the impact of four exercise modes (aerobic exercise, resistance exercise, aerobic combined with resistance multimodal exercise, and stretching) on the physical performance of cancer patients.
Rui Liu, XY Gao, Li Wang
doaj   +1 more source

Acute changes in passive muscle stiffness after resistance exercise: a narrative review of effects of program variables

Journal of Physical Fitness and Sports Medicine
Resistance exercise may empirically be believed to cause acute increases in passive muscle stiffness in sports and rehabilitation. An acute increase in muscle stiffness limits the joint range of motion (ROM) and may indirectly increase the risk of ...
Raki Kawama, Tatsuya Hojo, Taku Wakahara
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Secondary lymphoedema following cancer: Association with exercise barriers self-efficacy, and benefits of resistance and aerobic-based exercise [PDF]

, 2015
This research provides valuable insight into exercise barriers and prescription for individuals with cancer-related lymphoedema, particularly following breast cancer.
Buchan, Jena Kathryn
core  

Comparison and study of the effects of resistance exercise trainings with two different loadings with Omega3-6-9 supplement on Adiponectin and hsCRP in Healthy overweight young men

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim: The purpose of this study was to investigate the effectiveness of two types of resistance exercise training along with omega-3-6-9 supplementations on some risk factors of cardiovascular diseases.
keyvan ahmadi dehrashid, Marefat Siahkohian, Salahadin Ahmadi, Lotfali Bolboli   +3 more
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source