FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Exercise: A Powerful Tool to Manage Type 2 Diabetes in the Ageing Population [PDF]
European Medical Journal Diabetes, 2014 The aim of this paper is to highlight the evidence on the interrelationships between exercise and Type 2 diabetes mellitus (T2DM) in the ageing population. The evidence addressed in the specific literature is presented in three domains: aerobic exercise,
Silvano Zanuso
doaj
The effects of aerobic and resistance exercise on markers of large joint health in stable rheumatoid arthritis patients:a pilot study [PDF]
, 2015 Objective: exercise is beneficial for people with rheumatoid arthritis (RA). However, patients and health professionals have expressed concern about the possible detrimental effects of exercise on joint health.
Breslin, Anne +7 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
BMC GeriatricsBackground Regular exercise is emphasized for the improvement of functional capacity and independence of older adults. This study aimed to compare the effects of a dual-task resistance exercise program and resistance exercise on cognition, mood ...
Ji-Eun Baek +4 more
doaj +1 more source
High-intensity compared to moderate-intensity training for exercise initiation, enjoyment, adherence, and intentions: an intervention study [PDF]
, 2014 Background: Understanding exercise participation for overweight and obese adults is critical for preventing comorbid conditions. Group-based high-intensity functional training (HIFT) provides time-efficient aerobic and resistance exercise at self ...
Heinrich, Bryan S. +3 more
core +1 more source
A Home-Based Program Using Patterned Sensory Enhancement Improves Resistance Exercise Effects for Children With Cerebral Palsy [PDF]
, 2013 Tze‐Hsuan Wang +6 more
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Comparison of the Functional and Numerical Responses of Resistant versus Non-resistant Populations of the Copepod Acartia Hudsonica Fed the Toxic Dinoflagellate Alexandrium Tamarense [PDF]
, 2007 The functional and numerical responses of grazers are key pieces of information in predicting and modeling predator–prey interactions. It has been demonstrated that exposure to toxic algae can lead to evolved resistance in grazer populations.
Colin, Sean, Dam, Hans G.
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source