Results 251 to 260 of about 5,101,401 (348)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Additional Benefits of Creatine Supplementation with Physical Therapy and Resistance Exercise in Knee Osteoarthritis: A Randomized Controlled Trial. [PDF]

J Clin Med
Osama M, Afridi S, Bonnechère B.
europepmc   +1 more source

Increased fatigue resistance of respiratory muscles during exercise after respiratory muscle endurance training

, 2006
Samuel Vergès, Oliver Lenherr, Andrea C. Haner, Christian Schulz, Christina M. Spengler   +4 more
openalex   +1 more source

Resistance Exercise to Prevent and Manage Sarcopenia and Dynapenia

Annual Review of Gerontology and Geriatrics, 2016
B. Clark, Leatha A. Clark, T. Law
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Associations between expectations and responses to chronic resistance exercise in young adults with and without analogue generalized anxiety disorder. [PDF]

Sci Rep
Rice JM, Gordon BR, Lindheimer JB, Lyons M, Herring MP.   +4 more
europepmc   +1 more source

Factors influencing participation in a randomized controlled resistance exercise intervention study in breast cancer patients during radiotherapy [PDF]

, 2015
Sandra M Gollhofer, Joachim Wiskemann, Martina E. Schmidt, Oliver Klassen, Cornelia M. Ulrich, Jan Oelmann, Holger Hof, Karin Potthoff, Karen Steindorf   +8 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Randomised phase-2 screening trial of intermittent energy restriction plus resistance exercise versus resistance exercise alone during chemotherapy for advanced breast cancer. [PDF]

Br J Cancer
Harvie M, Pegington M, Howell A, Lim Y, Livingstone K, Rose D, McMullan D, Maxwell A, Barrett E, Sellers K, Krizak S, Howell SJ.   +11 more
europepmc   +1 more source

Association Between Prescribed Dosage of Resistance Exercise and Change in Pain and Physical Function in Knee Osteoarthritis: A Systematic Review With Meta‐Regression [PDF]

John de Wit, Travis Haber, Michelle Hall, Kim L. Bennell, Rana S. Hinman, Libby Spiers, Alexander J. Kimp, Andrea Dell’Isola, Alison R. Harmer, Martin van der Esch, Belinda J. Lawford   +10 more
openalex   +1 more source