Results 11 to 20 of about 8,603,806 (347)

Gene therapy with drug resistance genes [PDF]

open access: yesCancer Gene Therapy, 2005
A major side effect of cancer chemotherapy is myelosuppression. Expression of drug-resistance genes in hematopoietic stem cells (HSC) using gene transfer methodologies holds the promise of overcoming marrow toxicity in cancer chemotherapy. Adequate protection of marrow cells in cancer patients from myelotoxicity in this way would permit the use of ...
M, Zaboikin   +2 more
openaire   +2 more sources

Comprehensive profiling of serotypes, antimicrobial resistance and virulence of Salmonella isolates from food animals in China, 2015–2021

open access: yesFrontiers in Microbiology, 2023
IntroductionSalmonella is a ubiquitous foodborne pathogen and mainly transmitted to human farm-to-fork chain through contaminated foods of animal origin.MethodsIn this study, we investigated the serotypes, antimicrobial resistance and virulence of ...
Lili Guo   +13 more
doaj   +1 more source

Forecasting the dissemination of antibiotic resistance genes across bacterial genomes

open access: yesNature Communications, 2021
Antibiotic resistance spreads among bacteria through horizontal transfer of antibiotic resistance genes (ARGs). Here, we set out to determine predictive features of ARG transfer among bacterial clades.
M. Ellabaan   +4 more
semanticscholar   +1 more source

Globally distributed mining-impacted environments are underexplored hotspots of multidrug resistance genes

open access: yesThe ISME Journal, 2022
Mining is among the human activities with widest environmental impacts, and mining-impacted environments are characterized by high levels of metals that can co-select for antibiotic resistance genes (ARGs) in microorganisms.
Xinzhu Yi   +13 more
semanticscholar   +1 more source

Enhanced Degradation of Sulfamethoxazole (SMX) in Toilet Wastewater by Photo-Fenton Reactive Membrane Filtration

open access: yesNanomaterials, 2020
Pharmaceutical residuals are increasingly detected in natural waters, which made great threat to the health of the public. This study evaluated the utility of the photo-Fenton ceramic membrane filtration toward the removal and degradation of ...
Shaobin Sun   +5 more
doaj   +1 more source

Mobile Oxazolidinone Resistance Genes in Gram-Positive and Gram-Negative Bacteria

open access: yesClinical Microbiology Reviews, 2021
Seven mobile oxazolidinone resistance genes, including cfr, cfr(B), cfr(C), cfr(D), cfr(E), optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases, which confer a multiresistance phenotype that includes resistance to ...
S. Schwarz   +9 more
semanticscholar   +1 more source

Investigation of Antimicrobial Susceptibilities and Resistance Genes of Campylobacter Isolates from Patients in Edirne, Turkey

open access: yesIranian Journal of Public Health, 2022
Background: We aimed to determine the susceptibility of Campylobacter isolates obtained from patients to various antimicrobial agents and to investigate some related antimicrobial resistance genes.
Canan Eryıldız   +2 more
doaj   +1 more source

Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches

open access: yesWorld Journal of Microbiology & Biotechnology, 2022
Antimicrobial pharmaceuticals are classified as emergent micropollutants of concern, implying that even at low concentrations, long-term exposure to the environment can have significant eco-toxicological effects.
C. Mutuku, Z. Gazdag, S. Melegh
semanticscholar   +1 more source

ARDB--Antibiotic Resistance Genes Database [PDF]

open access: yesNucleic Acids Research, 2009
The treatment of infections is increasingly compromised by the ability of bacteria to develop resistance to antibiotics through mutations or through the acquisition of resistance genes. Antibiotic resistance genes also have the potential to be used for bio-terror purposes through genetically modified organisms. In order to facilitate the identification
Liu, Bo, Pop, Mihai
openaire   +2 more sources

PathoFact: a pipeline for the prediction of virulence factors and antimicrobial resistance genes in metagenomic data

open access: yesMicrobiome, 2021
Pathogenic microorganisms cause disease by invading, colonizing, and damaging their host. Virulence factors including bacterial toxins contribute to pathogenicity.
L. de Nies   +7 more
semanticscholar   +1 more source

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