Results 31 to 40 of about 1,162,589 (269)

Complex Interactions between Fungal Avirulence Genes and Their Corresponding Plant Resistance Genes and Consequences for Disease Resistance Management

Frontiers in Plant Science, 2017
During infection, pathogens secrete an arsenal of molecules, collectively called effectors, key elements of pathogenesis which modulate innate immunity of the plant and facilitate infection.
Yohann Petit-Houdenot, Isabelle Fudal
doaj   +1 more source

Global expression patterns of R-genes in tomato and potato

Frontiers in Plant Science, 2023
IntroductionAs key-players of plant immunity, the proteins encoded by resistance genes (R-genes) recognize pathogens and initiate pathogen-specific defense responses.
Janina K. von Dahlen, Janina K. von Dahlen, Kerstin Schulz, Kerstin Schulz, Jessica Nicolai, Laura E. Rose, Laura E. Rose   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Dynamic calcium–potassium balancing by KCNMA1 preserves the epithelial/mesenchymal hybrid state and modulates therapy response in ovarian cancer

Cell Death Discovery
Tumor cell plasticity and stemness fuel treatment resistance and cancer evolution into often incurable, metastatic terminal disease. To better understand these fundamental aspects of tumorigenesis, here we examine a potential role of KCNMA1, a calcium ...
Tereza Buchtova, Jirina Bartkova, Tatsuro Yamamoto, Marie Lund Bay, Allan Jensen, Susanne Krüger Kjær, Tuula Kallunki, Jiri Bartek, Robert Strauss   +8 more
doaj   +1 more source

Phased grapevine genome sequence of an Rpv12 carrier for biotechnological exploration of resistance to Plasmopara viticola

Frontiers in Plant Science, 2023
The downy mildew disease caused by the oomycete Plasmopara viticola is a serious threat for grapevine and can cause enormous yield losses in viticulture. The quantitative trait locus Rpv12, mediating resistance against P.
Bianca Frommer, Bianca Frommer, Sophia Müllner, Daniela Holtgräwe, Prisca Viehöver, Bruno Huettel, Reinhard Töpfer, Bernd Weisshaar, Eva Zyprian   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Correlation between the antibiotic resistance and virulence determinants of vancomycin-resistant enterococci: paradoxical involvement of vanA in phenotypic resistance to teicoplanin

Gut Pathogens
Background Antimicrobial resistance, particularly in clinical Enterococcus isolates, poses a serious global health threat because of difficult-to-treat nosocomial infections.
Rana M. Amr, Amr S. Bishr, Khaled M. Aboshanab, Nadia A. Hassouna   +3 more
doaj   +1 more source

Fusarium Yellows of Ginger (Zingiber officinale Roscoe) Caused by Fusarium oxysporum f. sp. zingiberi Is Associated with Cultivar-Specific Expression of Defense-Responsive Genes

Pathogens, 2023
Ginger (Zingiber officinale Roscoe) is an important horticultural crop, valued for its culinary and medicinal properties. Fusarium yellows of ginger, caused by Fusarium oxysporum f. sp.
Duraisamy Prasath, Andrea Matthews, Wayne T. O’Neill, Elizabeth A. B. Aitken, Andrew Chen   +4 more
doaj   +1 more source

Obesity genes and insulin resistance [PDF]

Current Opinion in Endocrinology, Diabetes and Obesity, 2010
The exploding prevalence of insulin resistance and Type 2 diabetes (T2D) linked to obesity has become an alarming public health concern. Worldwide, approximately 171 million people suffer from obesity-induced diabetes and public health authorities expect this situation to deteriorate rapidly. An interesting clinical population of 'metabolically healthy
Anna C, Belkina, Gerald V, Denis
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source