Results 11 to 20 of about 1,259,159 (318)
A large bioassay identifies Stb resistance genes that provide broad resistance against Septoria tritici blotch Disease in the UK [PDF]
, 2022 Septoria tritici blotch (STB) is one of the most damaging fungal diseases of wheat in Europe, largely due to the paucity of effective resistance genes against it in breeding materials.
Rudd, J. J. +4 more
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Antibiotics, 2023 The occurrence and spread of antibiotic resistance genes (ARGs) in environmental microorganisms, particularly in poly-extremophilic bacteria, remain underexplored and have received limited attention.
Ermias Sissay Balcha +6 more
doaj +1 more source
Discovery of the fourth mobile sulfonamide resistance gene
Microbiome, 2017 Background Over the past 75 years, human pathogens have acquired antibiotic resistance genes (ARGs), often from environmental bacteria. Integrons play a major role in the acquisition of antibiotic resistance genes.
Mohammad Razavi +5 more
doaj +1 more source
Gene expression and fractionation resistance [PDF]
BMC Genomics, 2014 Previous work on whole genome doubling in plants established the importance of gene functional category in provoking or suppressing duplicate gene loss, or fractionation. Other studies, particularly in Paramecium have correlated levels of gene expression with vulnerability or resistance to duplicate loss.Here we analyze the simultaneous effect of ...
Chen, Eric CH, Sankoff, David
openaire +2 more sources
Characteristics of powdery mildew and its importance for wheat grown in Poland
Plant Protection Science, 2020 Powdery mildew of grasses and cereals (Blumeria graminis) is a fungal plant disease which is caused by species of fungi from the Erysiphaceae order. B. graminis is a biotrophic parasite, biologically diverse parasite with a high degree of specialization ...
Aleksandra Pietrusińska, Anna Tratwal
doaj +1 more source
Resistance Genes Identified [PDF]
Cancer Discovery, 2017 Abstract A CRISPR-based screen of all 19,050 genes in the genome has revealed around 100 genes that cancer cells must express in order for T cells—and, thus, immunotherapies—to effectively recognize and kill tumors.
openaire +2 more sources
The evolution of disease resistance genes [PDF]
Plant Molecular Biology, 2000 Several common themes have shaped the evolution of plant disease resistance genes. These include duplication events of progenitor resistance genes and further expansion to create clustered gene families. Variation can arise from both intragenic and intergenic recombination and gene conversion. Recombination has also been implicated in the generation of
Richter, T E, Ronald, P C
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Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae : known and novel candidate genes [PDF]
, 2014 Background The elevated expression of enzymes with insecticide metabolism activity can lead to high levels of insecticide resistance in the malaria vector, Anopheles gambiae.
Simon C Wagstaff +19 more
core +1 more source
Evading resistance to gene drives [PDF]
Genetics, 2020 Abstract Gene drives offer the possibility of altering and even suppressing wild populations of countless plant and animal species, and CRISPR technology now provides the technical feasibility of engineering them. However, population-suppression gene drives are prone to select resistance, should it arise. Here, we develop mathematical
Richard Gomulkiewicz +2 more
openaire +2 more sources
Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin
Disease Models & Mechanisms, 2018 Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the ...
Francisco Javier García-Rodríguez +10 more
doaj +1 more source