Results 201 to 210 of about 8,603,806 (347)
Retrovirus insertion and transcriptional activation of the multidrug-resistance gene in leukemias treated by a chemotherapeutic agent in vivo [PDF]
Jun Nagayama +7 more
openalex +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Genetic profiling of bacterial leaf blight resistance genes in Bangladeshi rice varieties. [PDF]
Islam MS +5 more
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Multiplex Gene Editing and Effect Analysis of Yield, Fragrance, and Blast Resistance Genes in Rice. [PDF]
Guan S +6 more
europepmc +1 more source
Global analysis of the metaplasmidome: ecological drivers and spread of antibiotic resistance genes across ecosystems [PDF]
Didier Debroas
openalex +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Soil-borne legacy facilitates the dissemination of antibiotic resistance genes in soil-plant continua. [PDF]
Xiao Z +11 more
europepmc +1 more source

