Results 231 to 240 of about 8,603,806 (347)

Microbial interactions as the key to understanding and controlling environmental spread of antibiotic resistance genes. [PDF]

open access: yesNPJ Antimicrob Resist
Huang H   +11 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Antibiotic susceptibility pattern and resistance genes in Salmonella strains isolated from cattle. [PDF]

open access: yesBMC Vet Res
Malik MZ   +14 more
europepmc   +1 more source

Antibiotic resistance gene profiles at various treatment stages of a full-scale municipal sewage plant

open access: bronze, 2019
Ioanna Zerva   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Global landscape of antibiotic resistance genes in the human gut microbiome metagenome-assembled genomes. [PDF]

open access: yesBMC Microbiol
Wang C   +9 more
europepmc   +1 more source

Unraveling Effects of miRNAs Associated with APR Leaf Rust Resistance Genes in Hybrid Forms of Common Wheat (Triticum aestivum L.) [PDF]

open access: gold
Julia Spychała   +5 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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