Results 241 to 250 of about 8,603,806 (347)

Commensal Clostridia in the preterm gut as reservoirs of antimicrobial resistance: susceptibility profiles, and resistance genes. [PDF]

FEMS Microbiol Ecol
Delannoy J, Ferraris L, Labellie C, Dupire L, Ilavska D, Butel MJ, Barbut F, Aires J.   +7 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Prophage φEr670 and Genomic Island GI_Er147 as Carriers of Resistance Genes in <i>Erysipelothrix rhusiopathiae</i> Strains. [PDF]

Int J Mol Sci
Dec M, Zomer AL, Broekhuizen-Stins MJ, Urban-Chmiel R.   +3 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Effects of Florfenicol on Intestinal Structure, Microbial Community and Antibiotic Resistance Genes in <i>Penaeus vannamei</i>. [PDF]

Microorganisms
Wang G, Shi X, Yan Y, Xie J, Zhang D, Zhang H.   +5 more
europepmc   +1 more source

Relationships among Tenascin Expression, DNA Ploidy Patterns, and Multidrug Resistance Gene Product (P‐Glycoprotein) in Human Colon Carcinoma

, 1993
Isamu Sugawara, Jun Hirakoshi, Moriaki Kusakabe, Atsuko Masunaga, Shinji Itoyama, Teruyo Sakakura   +5 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reply to: Giant virus genomes are unlikely to be reservoirs of antibiotic resistance genes. [PDF]

Nat Commun
Yi X, Liang JL, Li JT.
europepmc   +1 more source

Degradation of Extracellular Antibiotic Resistance Genes with UV254 Treatment.

Environmental Science and Technology, 2017
P. Chang, Brianna Juhrend, T. Olson, C. Marrs, K. Wigginton   +4 more
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source