Results 271 to 280 of about 1,259,159 (318)
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Nonhost resistance genes and race-specific resistance
Trends in Microbiology, 1993Apart from physical barriers, plants have two major types of defense against potential pathogens. In 'race-specific' resistance, plants match single mendelian resistance genes with the 'avirulence' genes possessed by races of a pathogen. Plants also employ the more complex and evolutionarily more robust system of 'nonhost resistance' against a broad ...
L A, Hadwiger, D E, Culley
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Co-resistance: an opportunity for the bacteria and resistance genes
Current Opinion in Pharmacology, 2011Co-resistance involves transfer of several genes into the same bacteria and/or the acquisition of mutations in different genetic loci affecting different antimicrobials whereas pleiotropic resistance implies the same genetic event affecting several antimicrobials.
Canton, R
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Gene Amplification and Insecticide Resistance
Annual Review of Entomology, 1991Recapitulation des travaux portant sur le mecanisme de resistance des insectes face aux substances toxiques, base sur l'amplification des genes de resistance.
A L, Devonshire, L M, Field
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Current Opinion in Plant Biology, 1998
Plant resistance genes are highly polymorphic and have diverse recognition specificities. These genes often occur as members of clustered gene families that have evolved through duplication and diversification. Regions of nucleotides conserved between family members and flanking sequences facilitate equal or unequal recombination events.
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Plant resistance genes are highly polymorphic and have diverse recognition specificities. These genes often occur as members of clustered gene families that have evolved through duplication and diversification. Regions of nucleotides conserved between family members and flanking sequences facilitate equal or unequal recombination events.
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Myeloprotection with drug-resistance genes
The Lancet Oncology, 2002One of the many applications of gene transfer for cancer gene therapy is the transfer of drug-resistance genes into bone-marrow stem cells for myeloprotection. Protection of the hosts' bone marrow should allow for dose escalation that may be useful for eradicating minimal residual disease in a post-transplant situation.
Debabrata, Banerjee, Joseph R, Bertino
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Aspirin resistance and a single gene
The American Journal of Cardiology, 2005This study examined the association of single nucleotide polymorphisms in 4 candidate genes in a cohort of subjects with aspirin resistance. Aspirin resistance was significantly associated with genetic variation in the platelet surface adenosine 5-diphosphate receptor gene P2Y1.
Brian K, Jefferson +6 more
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Candidate Genes for Insulin Resistance
Diabetes Care, 1996Insulin resistance confers increased susceptibility to NIDDM, atherosclerotic cardiovascular disease, ovarian hyperandrogenism, and possibly hypertension. Insulin resistance is largely inherited, in rare cases as a monogenic disorder or more commonly as a complex trait.
D E, Moller, C, Bjørbaek, A, Vidal-Puig
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Plant nematode resistance genes
Current Opinion in Plant Biology, 1999Root-knot and cyst nematodes cause severe damage to crops throughout the world. Genes conferring resistance against nematodes have been identified in many plant species and several of these have been, or soon will be, cloned. Nematode biotypes that can infect resistant plants have been identified.
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Evolving disease resistance genes
Current Opinion in Plant Biology, 2005Defenses against most specialized plant pathogens are often initiated by a plant disease resistance gene. Plant genomes encode several classes of genes that can function as resistance genes. Many of the mechanisms that drive the molecular evolution of these genes are now becoming clear.
Blake C, Meyers +2 more
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ACTH Resistance: Genes and Mechanisms
2013ACTH resistance is a rare disorder typified by familial glucocorticoid deficiency (FGD), a genetically heterogeneous disease. Previously, genetic defects in FGD have been identified in the ACTH receptor gene (MC2R), its accessory protein (MRAP) and the steroidogenic acute regulatory protein gene (STAR).
E, Meimaridou +5 more
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