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In Search of AIDS-Resistance Genes
Scientific American, 1997Focuses on studies conducted on persons infected with the human immunodeficiency virus (HIV) and how genes attribute to these persons part or full resistance to acquired immunodeficiency syndrome (AIDS). Number of persons who died from AIDS in the United States; Why some individuals escape HIV infection despite being at high risk.
O'Brien, Stephen J., Dean, Michael
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PLANT DISEASE RESISTANCE GENES
Annual Review of Plant Physiology and Plant Molecular Biology, 1997▪ Abstract In “gene-for-gene” interactions between plants and their pathogens, incompatibility (no disease) requires a dominant or semidominant resistance (R) gene in the plant, and a corresponding avirulence (Avr) gene in the pathogen. Many plant/pathogen interactions are of this type.
Kim E., Hammond-Kosack +1 more
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Genes for frost resistance in wheat
Euphytica, 2001Wheat varieties differ in their responses to low temperatures. Genetic studies on frost resistance in wheat are difficult because the effects are quantitative in nature and thus require precise genetic material and reproducible experimental conditions.
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A novel gene for rust resistance
Trends in Plant Science, 2003The Rpg1 gene, which has provided North American cultivars of barley with resistance to the stem rust fungus Puccinia graminis f.sp. tritici for more than 60 years, has been cloned. A single copy of the gene can confer resistance to a susceptible barley variety.
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Chemoprotection by Transfer of Resistance Genes
2009Dose-limiting toxicity of chemotherapeutic agents, i.e., myelosuppression, can limit their effectiveness. The transfer and expression of drug-resistance genes might decrease the risks associated with acute hematopoietic toxicity. Protection of hematopoietic stem/progenitor cells by transfer of drug-resistance genes provides the possibility of ...
Tulin, Budak-Alpdogan, Joseph R, Bertino
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Resistance gene analogs are candidate markers for disease-resistance genes in grape (Vitis spp.)
Theoretical and Applied Genetics, 2002A set of NBS-containing sequences was isolated from genomic DNA of two grape species ( Vitis amurensis and Vitis riparia) and characterised in a panel of Vitis genotypes carrying different levels of resistance against downy mildew and other diseases. A PCR-mediated approach made use of degenerate primers designed on conserved regions encoding known R ...
DI GASPERO, Gabriele, CIPRIANI, Guido
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Expression of Resistance Genes in Acute Leukemia
Leukemia & Lymphoma, 1994To evaluate the frequency and the prognostic value of different mechanisms of drug resistance in acute leukemias, we investigated the expression of mdr1 by immunocytochemistry, mRNA slot blot or RT-PCR in 182 cases of adult acute myeloid and 37 cases of adult lymphoblastic leukemia.
Zhou D. -C. +6 more
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