Results 141 to 150 of about 810,262 (267)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The effect of the erythropoietin resistance index on brain hemorrhage and infarction risk in maintenance hemodialysis patients: a retrospective cohort study. [PDF]

PeerJ
Liu M, Ren K, Wang Q, Zhao C, Ren Z, Bai J, Cao N.   +6 more
europepmc   +1 more source

The Antimicrobial Resistance Index and Fournier Gangrene Severity Index of Patients Diagnosed with Fournier's Gangrene in a Tertiary Hospital in North Eastern Romania. [PDF]

Medicina (Kaunas), 2023
Puia D, Gheorghincă Ş, Pricop C.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The association between baseline and long-term status of metabolic score for insulin resistance index and the incidence of cardiometabolic multimorbidity. [PDF]

BMC Public Health
Yang M, Liu J, Shen S, Shen Q, Liu Y, Qian Y.   +5 more
europepmc   +1 more source

A nonlinear associations of metabolic score for insulin resistance index with incident diabetes: A retrospective Chinese cohort study. [PDF]

Front Clin Diabetes Healthc, 2022
Chen Z, Huang C, Zhou Z, Zhang Y, Xu M, Tang Y, Fan L, Feng K.   +7 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A predictive endocrine resistance index accurately stratifies luminal breast cancer treatment responders and nonresponders. [PDF]

J Clin Invest
Zhang G, Jurinovic V, Bartels S, Christgen M, Christgen H, Kandt LD, Mishieva L, Ni H, Raap M, Klein J, Katzke AL, Hofmann W, Steinemann D, Kates RE, Gluz O, Graeser M, Kümmel S, Nitz U, Plass C, Lehmann U, Zu Eulenburg C, Mansmann U, Gerhäuser C, Harbeck N, Kreipe HH.   +24 more
europepmc   +1 more source

The Relationship Between Admission Insulin Resistance Index (AIRI) and In-Hospital Outcome in Non-Diabetic Acute Coronary Syndrome. [PDF]

J ASEAN Fed Endocr Soc, 2023
Muntari J, Umar H, Tandean P, Bakri S, Sanusi H, Tabri NA, Seweng A.   +6 more
europepmc   +1 more source

Index of Microcirculatory Resistance and Infarct Size

JACC: Cardiovascular Imaging, 2019
William F, Fearon, Rajesh, Dash
openaire   +2 more sources