Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]
Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
core +1 more source
Effects of in vitro‐induced drug resistance on the virulence of Streptococcus
This study aimed to evaluate the effects of in vitro‐induced drug resistance on the virulence of Streptococcus. Micro‐dilution method was used to determine the minimal inhibitory concentration (MIC).
Yue‐Xia Ding +6 more
doaj +1 more source
Induction of Gentamicin Resistance by Visible Light [PDF]
Recent studies have demonstrated the ability of visible light or phototherapy to modify the intracellular DNA of prokaryotic and eukaryotic cells. The present study was undertaken to determine the effect of light used in phototherapy on antibiotic resistance in prokaryotic cells using tester strains of gentamicin-sensitive Escherichia coli and ...
M C, Harris +3 more
openaire +2 more sources
The magneto-optical imaging technique is used to visualize the penetration of the magnetic induction in YBa$_{2}$Cu$_{3}$O$_{7-\delta}$ thin films during surface resistance measurements. The in-situ surface resistance measurements were performed at 7 GHz
Bruno Marcilhac +6 more
core +2 more sources
Genome sequencing analysis of Streptomyces coelicolor mutants that overcome the phosphate-depending vancomycin lethal effect [PDF]
Background Glycopeptide antibiotics inhibit bacterial cell-wall synthesis, and are important for the treatment of infections caused by multi drug-resistant strains of enterococci, streptococci and staphylococci.
Santos Beneit, Fernando
core +1 more source
Not only P-glycoprotein: amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins [PDF]
The development of drug resistance continues to be a dominant hindrance toward curative cancer treatment. Overexpression of a wide-spectrum of ATP-dependent efflux pumps, and in particular of ABCB1 (P-glycoprotein or MDR1) is a well-known resistance ...
Assaraf, Yehuda G. +4 more
core +1 more source
A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. [PDF]
The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic targets for the treatment of obesity and associated insulin resistance. Here we show that acute
Ahmadian, Maryam +16 more
core +2 more sources
Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunity. [PDF]
It is an apparent conundrum how plants evolved effector-triggered immunity (ETI), involving programmed cell death (PCD), as a major defence mechanism against biotrophic pathogens, because ETI-associated PCD could leave them vulnerable to necrotrophic ...
Dong, Xinnian +8 more
core +1 more source
Systemic resistance induction in ‘Ortanique’ tangor
This study aimed to evaluate the quality of ‘Ortanique’ tangor, in the post-harvest and refrigerated storage after application of pre-harvest resistance inducers, in the 2015 and 2016 crops.
Marines Batalha Moreno Kirinus +4 more
doaj +1 more source
Environmental stress responses in Lactococcus lactis [PDF]
Bacteria can encounter a variety of physical conditions during their life. Bacterial cells are able to survive these (often adverse) conditions by the induction of specific or general protection mechanisms. The lactic acid bacterium Lactococcus lactis is
Kok, Jan, +2 more
core +3 more sources

