Results 21 to 30 of about 2,321,454 (339)

The cyclin-dependent kinase inhibitor p57(Kip2) is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer [PDF]

, 2012
Carboplatin remains a first-line agent in the management of epithelial ovarian cancer (EOC). Unfortunately, platinum-resistant disease ultimately occurs in most patients.
A Bali, C Beretta, D P Lovell, E Papacharalbous, E Rosenberg, G D’Andrilli, H M Coley, HM Coley, I-S Song, K Madhuri, MA Levesque, N A M Safuwan, N Syed, N Syed, P Chivers, P Vlachos, P Zhang, PS Larson, RM Glasspool, S Butler-Manuel, SH Wei, ST Kim, T Crook, T Giannopoulos, T Kobatake, V Masciullo, W Roeb, Y Ma   +27 more
core   +1 more source

Framework for an expert evaluation for the evolution of weed resistance

Julius-Kühn-Archiv, 2014
The apparent rate of evolution of resistance of weeds to herbicides has increased substantially over the past decade. Data suggests phenotypic expression is affected by the mechanism of action of the herbicide, the taxonomy of the weed, the extent and ...
Vencill, William, Nichols, Robert, Webster, Theodore, Moss, Stephen   +3 more
doaj   +1 more source

Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa [PDF]

, 2014
Substantial amounts of data have been generated from patient management and academic exercises designed to better understand the human immunodeficiency virus (HIV) epidemic and design interventions to control it.
Bester, Armand, Chetty, Terusha, Danaviah, Siva, De Oliveira, Tulio, Goedhals, Dominique, Iwuji, Collins, Lessells, Richard, Manasa, Justen, McGrath, Nuala, Moodley, Pravi, Naidu, Kevindra, Rossouw, Theresa, Seebregts, Christopher J, Singh, Lavanya, Skingsley, Andrew, Stott, Katharine, Van Vuuren, Cloete, Van Zyl, Gert   +17 more
core   +3 more sources

Characterization of Asian Corn Borer Resistance to Bt Toxin Cry1Ie

Toxins, 2017
A strain of the Asian corn borer (ACB), Ostrinia furnacalis (Guenée), has evolved >800-fold resistance to Cry1Ie (ACB-IeR) after 49 generations of selection. The inheritance pattern of resistance to Cry1Ie in ACB-IeR strain and its cross-resistance to
Yueqin Wang, Jing Yang, Yudong Quan, Zhenying Wang, Wanzhi Cai, Kanglai He   +5 more
doaj   +1 more source

Management of resistant hypertension [PDF]

Canadian Medical Association Journal, 2015
In their review, Padwal and colleagues[1][1] made an interesting and important omission. Variants of Liddle syndrome (genetic mutations affecting the renal tubular epithelial sodium channel, ENac, causing salt and water retention and loss of potassium), are far commoner than most physicians ...
openaire   +3 more sources

Overlapping Residual Herbicides for Control of Photosystem (PS) II- and 4-Hydroxyphenylpyruvate Dioxygenase (HPPD)-Inhibitor-Resistant Palmer amaranth (Amaranthus palmeri S. Watson) in Glyphosate-Resistant Maize

Frontiers in Plant Science, 2018
A Palmer amaranth (Amaranthus palmeri S. Watson) biotype has evolved resistance to photosystem (PS) II- (atrazine) and 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibiting herbicides (mesotrione, tembotrione, and topramezone) in maize seed production ...
Parminder S. Chahal, Zahoor A. Ganie, Amit J. Jhala   +2 more
doaj   +1 more source

Identifying Current and Missing Knowledge in the Control of Pyrethroid-Resistant Triatoma Infestans, Vector of Chagas Disease [PDF]

, 2017
Triatomines are blood-sucking bugs that occur mainly in Latin America. They are vectors of Trypanosoma cruzi, the parasite that causes Chagas disease.
Picollo, Maria Ines, Roca Acevedo, Gonzalo   +1 more
core   +1 more source

Complex Interactions between Fungal Avirulence Genes and Their Corresponding Plant Resistance Genes and Consequences for Disease Resistance Management

Frontiers in Plant Science, 2017
During infection, pathogens secrete an arsenal of molecules, collectively called effectors, key elements of pathogenesis which modulate innate immunity of the plant and facilitate infection.
Yohann Petit-Houdenot, Isabelle Fudal
doaj   +1 more source

Imidacloprid Resistance Challenges in Brazilian Strains of Drosophila suzukii (Diptera: Drosophilidae)

Insects
Drosophila suzukii (Matsumura) is a relevant pest affecting berries and stone fruits globally, including in the Neotropical region, where its invasion was reported about a decade ago.
Felipe Andreazza, Flávio Roberto Mello Garcia, Pedro Bento da Silva, Lucas Bretas Barbosa, Joel Marques de Oliveira, Gabriel Netto Araújo, Eugenio E. Oliveira   +6 more
doaj   +1 more source

Defining Integrated Weed Management: A Novel Conceptual Framework for Models

Agronomy, 2021
Weed population dynamics models are an important tool for predicting the outcome of alternative Integrated Weed Management (IWM) scenarios. The growing problem of herbicide resistance has increased the urgency for these tools in the design of sustainable
Jonathan Storkey, Joseph Helps, Richard Hull, Alice E. Milne, Helen Metcalfe   +4 more
doaj   +1 more source