Results 51 to 60 of about 2,218,856 (342)
Defining and Managing Imatinib Resistance [PDF]
Hematology, 2006 AbstractWhile imatinib is highly effective therapy, with improving prospects over time for sustained remission and potential to severely limit or eliminate disease progression and transformation, a minority of patients either fail or respond suboptimally to imatinib; as well, disease eradication may not be possible with imatinib.
openaire +3 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Chlorophyll fluorescence response to herbicide stress in Alopecurus myosuroides
Julius-Kühn-Archiv, 2016 Herbicide resistance has been a widely spread problem all over the world. The resistance detection is usually complicated and financial resources consuming. A sensor based monitoring of herbicide resistance would make the resistance detection much faster
Wang, Pei, Li, Hui, Gerhards, Roland
doaj +1 more source
The middle manager: Friend or foe of employee involvement [PDF]
, 1996 Middle management resistance has been frequently identified as a significant barrier to the success of employee involvement practices. This paper reviews evidence from the literature and from 12 case studies on the role played by middle managers in ...
Fenton-O'Creevy, Mark
core
Management of drug-resistant tuberculosis
The Lancet, 2019 Drug-resistant tuberculosis is a major public health concern in many countries. Over the past decade, the number of patients infected with Mycobacterium tuberculosis resistant to the most effective drugs against tuberculosis (ie, rifampicin and isoniazid), which is called multidrug-resistant tuberculosis, has continued to increase.
Dumitru Chesov +7 more
openaire +4 more sources
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018 Treatment resistance is a persistent neurochemical condition characterized by the presence of the «hybrid», combined pathological and drug metabolism.
V. L. Kozlovskii
doaj
Insuring the Stewardship of Bt Corn: "A Carrot" versus "A Stick"
Journal of Agricultural and Resource Economics, 2002 Subsidies and fines are compared to voluntary and mandatory refuge insurance (insurance for pest damage on Bt corn refuge) as mechanisms for securing grower compliance with EPA refuge mandates. A conceptual model partially ranks mechanisms.
Paul D. Mitchell +3 more
doaj +1 more source
Herbicide Resistance in Plants
Plants, 2020 Herbicide resistance in weeds is perhaps the most prominent research area within the discipline of weed science today. Incidence, management challenges, and the cost of multiple-resistant weed populations are continually increasing worldwide.
Hugh J Beckie
doaj +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source