Results 51 to 60 of about 855,776 (315)
Managing the evolution of herbicide resistance
Pest Management Science, 2015 Abstract BACKGROUND Understanding and managing the evolutionary responses of pests and pathogens to control efforts is essential to human health and survival.
Evans, Jeffrey A +6 more
openaire +2 more sources
Evidence-based resistance management: a review of existing evidence
, 2015 The control of fungal plant pathogens has been characterised by repeated cycles of introduction of new fungicides and for many of them a subsequent loss of efficacy due to the emergence and selection of resistant pathogen strains. Several strategies have
Oliver, R. +11 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Management of Resistant Hypertension
Annual Review of MedicineResistant hypertension (RH) is a severe form of hypertension associated with increased cardiovascular risk. Although true RH affects less than 10% of the patients receiving antihypertensive therapy, the absolute number is high and continues to increase.
Lucas, Lauder +2 more
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Managing drug resistant tuberculosis [PDF]
BMJ, 2008 #### Summary points Antituberculosis drug resistance is increasing both in the United Kingdom and internationally.1 2 It has come to greater public attention with the emergence of extensively drug resistant tuberculosis (box 1) in South Africa, where an outbreak proved rapidly fatal among people with advanced HIV infection.3 In this article we review ...
Grant, Alison +2 more
openaire +4 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Susceptibility of soybean looper to lufenuron and spinosad
Arquivos do Instituto Biológico: The soybean looper (Chrysodeixis includens) is an important defoliation pest in crops such as soybean and cotton in Brazil. Its main control tactic is chemical insecticides.
Lucas Ferraz de Queiroz +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Julius-Kühn-Archiv, 2011 Anticoagulant resistance was first discovered in UK Norway rats (Rattus norvegicus Berk.) in 1958 and has been present ever since. The possible detrimental impact of resistance on effective rodent control was quickly recognised and, for almost three ...
Buckle, A.
doaj +1 more source