Results 61 to 70 of about 1,545,817 (309)
, 2019 Over the past few years, California became the setting for shocking tales of sex inequality and abuse in Hollywood and Silicon Valley. Decades after women achieved educational parity. men still run the corporate world.
Rosenblum, Darren
core +1 more source
Conformational Changes in the Metallo-β-lactamase ImiS During the Catalytic Reaction: An EPR Spectrokinetic Study of Co(II)-Spin Label Interactions [PDF]
, 2008 Metallo-β-lactamases are responsible for conferring antibiotic resistance on certain pathogenic bacteria. In consequence, the search for inhibitors that may be useful in combating antibiotic resistance has fueled much study of the active sites of these ...
Bennett, Brian +3 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Activity of Ukrainian Nationalists in Yuzivka (Donetsk) City in 1941–1943
Київські історичні студіїThe activities of the OUN(b) in eastern Ukraine, in particular in the Donetsk region, are becoming relevant in light of current events in Ukraine. The narrow topic of research on this issue in the eastern territories has not yet received sufficient ...
Liudmyla Lytvynenko-Anpilova
doaj +1 more source
Energy Science & Engineering, 2019 The increase in extraction height will increase the mining‐induced overlying strata failure height. In this scenario, the strata pressure behavior is strong in a fully mechanized face with large mining height (FMFLMH), which frequently causes coal wall ...
Bo Li, Yunpei Liang, Quanle Zou
doaj +1 more source
Globalising resistance: social movement activism in Malawi [PDF]
, 2011 Attendant with the rise of the good governance discourse of the 1990s and beyond, contemporary research on social activism in Africa has tended to be rooted in normalised conceptions of civil society operating in partnership with the state.
Gaynor, Niamh
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Resistance Operating Concept as a Tool for Increasing the Resilience of the State
Vojenské rozhledyThe article describes the issue of implementing the Resistance Operating Concept as part of a comprehensive approach to ensuring the defense of the state and its resilience.
Radek Dubec +2 more
doaj +1 more source
Effects of Laryngeal Restriction on Pharyngeal Peristalsis and Biomechanics: Clinical Implications [PDF]
, 2016 To date, rehabilitative exercises aimed at strengthening the pharyngeal muscles have not been developed due to the inability to successfully overload and fatigue these muscles during their contraction, a necessary requirement for strength training.
Balasubramanian, Gokulakrishnan +5 more
core +2 more sources