Results 81 to 90 of about 4,323,884 (296)

Antibiotic resistance: it’s bad, but why isn’t it worse?

open access: yesBMC Biology, 2017
Antibiotic natural products are ancient and so is resistance. Consequently, environmental bacteria harbor numerous and varied antibiotic resistance elements.
Nicholas Waglechner, Gerard D. Wright
doaj   +1 more source

Limitations of vehicle movement resistances: rolling resistance

open access: yesAUTOBUSY – Technika, Eksploatacja, Systemy Transportowe, 2018
In the paper limitations and exemplary methods of rolling resistance minimization are described. Changes of value of rolling resistance coefficient during years and values for exemplary rolling pairs are presented. Conclusions about future progress are formulated.
Aleksandra Pindel   +2 more
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

New Unity Movement Bulletin

open access: yes, 2003
The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid ...

core   +1 more source

Electromyographic comparison of the barbell deadlift using constant versus variable resistance in healthy, trained men.

open access: yesPLoS ONE, 2019
Variable, external resistance is proposed to increasingly augment the muscular stress throughout a dynamic movement. However, it is uncertain how different levels of variable resistance affect the activation in the deadlift.
Vidar Andersen   +6 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Slovak National Uprising and the USSR (On the 80th Anniversary)

open access: yesСлавянский мир в третьем тысячелетии
The article is dedicated to the largest event in Slovak history during the Second World War – the Slovak National Uprising (SNU) and is based on the materials from the Russian Foreign Policy Archive, published documents, memoires and scientific research.
Elena P. Serapionova
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Minutes of the New Unity Movement, South Peninsula Branch, meeting held on 27 September 2009

open access: yes, 2009
Minutes of the New Unity Movement, South Peninsula Branch, meeting held on Sunday, 27 September ...
New Unity Movement
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

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