Results 91 to 100 of about 1,545,817 (309)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Youth Anti-Soviet Resistance Movement in Lithuania in the Seventies and Eighties
Genocidas ir Rezistencija, 1998 The formation of a resistance movement in the totalitarian Soviet system is a unique phenomenon. In Lithuania, the resistance has never been completely absent.
Živilė Račkauskaitė
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Antibiotic resistance: it’s bad, but why isn’t it worse?
BMC Biology, 2017 Antibiotic natural products are ancient and so is resistance. Consequently, environmental bacteria harbor numerous and varied antibiotic resistance elements.
Nicholas Waglechner, Gerard D. Wright
doaj +1 more source
Nonlinear Transport of Graphene in the Quantum Hall Regime
, 2016 We have studied the breakdown of the integer quantum Hall (QH) effect with fully broken symmetry, in an ultra-high mobility graphene device sandwiched between two single crystal hexagonal boron nitride substrates.
Chen, Jian-Hao +8 more
core +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
PLoS ONE, 2019 Variable, external resistance is proposed to increasingly augment the muscular stress throughout a dynamic movement. However, it is uncertain how different levels of variable resistance affect the activation in the deadlift.
Vidar Andersen +6 more
doaj +1 more source
Movement Artefact Resistant Photoplethysmographic Probe
Elektronika ir Elektrotechnika, 2014 Photoplethysmogram (PPG) is an exceptionally informative diagnostic tool, but the signal registered by wearable devices usually is corrupted, because the probe is affected by the external force and moves with respect to the point of the measurement during the physical activities of the human.
Gircys, R. +3 more
openaire +2 more sources
The Anti-War Adoption of Lord of the Rings [PDF]
, 2015 Ten years after Tolkien’s Lord of the Rings trilogy was first published in 1954, an unexpected party discovered Middle-earth. America’s counterculture adopted the series, despite its largely conservative, patriarchal, and militant ideologies.
Spencer, Kayla
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source