Results 31 to 40 of about 33,766 (287)
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost +10 more
wiley +1 more source
Resisting Bacterial Drug Resistance [PDF]
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire +2 more sources
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender +17 more
wiley +1 more source
Results from new fungus-tolerant grapevine varieties for Organic Viticulture [PDF]
Two red and three white new fungus-tolerant grape varieties were tested within a period of five years. REGENT, RONDO, JOHANNITER and Gf 48-12 show a better wine quality than PINOT NOIR or SILVANER and can be recommended for Organic Viticulture as well ...
Knott, R., Schottdorf, W., Schwab, A. L.
core
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source
The Role of Intensive Insulin Therapy on Superoxide Dismutase (Sod), Tumor Necrosis Factor-? (Tnf-?), and Interleukin-6 (Il-6) on Hyperglycemia in Critically Ill Patients [PDF]
Hyperglycemia and insulin resistance are common in critically ill patientsin the ICU, although they have not previously had diabetes. It has been reportedthat pronounced hyperglycemia may lead to complications in such patients, andcause the reactive ...
Bagianto, H. (Hari) +3 more
core
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
BRAIDOTTI, Rosi (2017): Per una politica affermativa. Itinerari etici. Milan: Mimesis.
Is it possible to imagine an affirmative political theory and practice today? This is the central issue addressed by the nomadic philosopher Rosi Braidotti is her new book, still to be translated, Per una politica affermativa.
Myriam Hernández Domínguez
doaj +1 more source
El problema converso en la literatura del Renacimiento [PDF]
El autor trata la resistencia de los judíos conversos a adoptar las costumbres a las que les obligaba su nueva religión, planteando si se dió dicha resistencia también en algunas obras literarias, especialmente La lozana andaluza de Francisco Delicado ...
MacKay, Angus
core +1 more source
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source

