Results 1 to 10 of about 1,531 (137)

Actualización sobre la resistencia antimicrobiana en instituciones de salud de nivel III y IV en Colombia entre enero del 2018 y diciembre del 2021 [PDF]

Biomédica: revista del Instituto Nacional de Salud, 2023
Introducción. El comportamiento de la resistencia antimicrobiana es fundamental en el mejoramiento y ajuste de los programas de optimización de uso de antimicrobianos, la implementación de las guías terapéuticas y las precauciones que limitan la ...
Elsa De La Cadena, Christian José Pallares, Juan Carlos García-Betancur, Jessica A. Porras, María Virginia Villegas   +4 more
doaj   +2 more sources

A whole‐cell hypersensitive biosensor for beta‐lactams based on the AmpR‐AmpC regulatory circuit from the Antarctic Pseudomonas sp. IB20

Microbial Biotechnology
Detecting antibiotic residues is vital to minimize their impact. Yet, existing methods are complex and costly. Biosensors offer an alternative. While many biosensors detect various antibiotics, specific ones for beta‐lactams are lacking.
Sebastián Higuera‐Llantén, Manuel Alcalde‐Rico, Felipe Vasquez‐Ponce, Claudia Ibacache‐Quiroga, Jesús Blazquez, Jorge Olivares‐Pacheco   +5 more
doaj   +2 more sources

Antimicrobial Stewardship Programs in Latin America and the Caribbean: A Story of Perseverance, Challenges, and Goals

Antibiotics, 2023
Antimicrobial resistance is one of the major global health threats. Antimicrobial stewardship (AMS) has been set as a priority within international action plans to combat this issue.
Natalia Restrepo-Arbeláez, Juan Carlos Garcia-Betancur, Christian Jose Pallares, María Virginia Villegas   +3 more
doaj   +1 more source

Molecular Analysis of Polymyxin Resistance among Carbapenemase-Producing Klebsiella pneumoniae in Colombia

Antibiotics, 2021
Polymyxin resistance in Klebsiella pneumoniae has been attributed to mutations in mgrB, phoPQ, pmrAB, and crrAB and to the presence of mcr plasmid-mediated genes. Herein, we describe the molecular characteristics of 24 polymyxin- and carbapenem-resistant
Elsa De La Cadena, María Fernanda Mojica, Juan Carlos García-Betancur, Tobías Manuel Appel, Jessica Porras, Christian José Pallares, Juan Sebastián Solano-Gutiérrez, Laura J. Rojas, María Virginia Villegas   +8 more
doaj   +1 more source

Molecular Mechanisms of Resistance to Ceftazidime/Avibactam in Clinical Isolates of Enterobacterales and Pseudomonas aeruginosa in Latin American Hospitals

mSphere, 2023
Ceftazidime-avibactam (CZA) is the combination of a third-generation cephalosporin and a new non-β-lactam β-lactamase inhibitor capable of inactivating class A, C, and some D β-lactamases. From a collection of 2,727 clinical isolates of Enterobacterales (
María Fernanda Mojica, Elsa De La Cadena, Juan Carlos García-Betancur, Jessica Porras, Isabella Novoa-Caicedo, Laura Páez-Zamora, Christian Pallares, Tobias Manuel Appel, Marcela A. Radice, Paulo Castañeda-Méndez, Ana C. Gales, José M. Munita, María Virginia Villegas   +12 more
doaj   +1 more source

Microbiological and Clinical Aspects of Raoultella spp.

Frontiers in Public Health, 2021
The genus Raoultella was established in 2001. Species of Raoultella and Klebsiella share many ecological, biochemical, clinical, and microbiological features.
Tobias M. Appel, Tobias M. Appel, Natalia Quijano-Martínez, Elsa De La Cadena, María F. Mojica, María Virginia Villegas   +5 more
doaj   +1 more source

Evaluation of Allplex™ Entero-DR assay for detection of antimicrobial resistance determinants from bacterial cultures

BMC Research Notes, 2020
Objective To evaluate the sensitivity and specificity of the Allplex™ Entero-DR, a quantitative PCR-based method, for the detection of β-lactamase-encoding genes and vancomycin-resistance determinants in 156 previously characterized Gram-negative bacilli
María Fernanda Mojica, Elsa De La Cadena, Adriana Correa, Tobias Manuel Appel, Christian José Pallares, María Virginia Villegas   +5 more
doaj   +1 more source

Genomic Analysis of CTX-M-Group-1-Producing Extraintestinal Pathogenic E. coli (ExPEc) from Patients with Urinary Tract Infections (UTI) from Colombia

Antibiotics, 2020
Background: The dissemination of the uropathogenic O25b-ST131 Escherichia coli clone constitutes a threat to public health. We aimed to determine the circulation of E.
Elsa De La Cadena, María Fernanda Mojica, Nathaly Castillo, Adriana Correa, Tobias Manuel Appel, Juan Carlos García-Betancur, Christian José Pallares, María Virginia Villegas   +7 more
doaj   +1 more source

Antimicrobial stewardship programs in seven Latin American countries: facing the challenges

BMC Infectious Diseases, 2023
Background Studies have shown that more than 50% of the antibiotics used in hospitals are unnecessary or inappropriate and, that antimicrobial resistance may cost up to 20 billion USD in excess medical costs each year.
Christian José Pallares, Jessica Porras, Elsa De La Cadena, Juan Carlos García-Betancur, Natalia Restrepo-Arbeláez, Sara María Cobo Viveros, Wanda Cornistein, Paulo Castañeda-Méndez, Luis Cuellar, Diogo Boldim-Ferreira, Jorge Chaverri-Murillo, Jaime A. Labarca, María Virginia Villegas   +12 more
doaj   +1 more source

In vitro antimicrobial activity of Bixa orellana L. leaves extract against anaerobic bacteria  associated to bacterial vaginosis and Lactobacillus spp.

Revista Peruana de Medicina Experimental y Salud Pública, 2022
Objective. To describe the in vitro antimicrobial activity of the methanolic extract of Bixa orellana L. leaves against anaerobic bacteria associated to bacterial vaginosis and  Lactobacillus spp. Materials and methods.
Jenny Marcas, Liz Romero, Oswaldo Tipiani, Steev Loyola, Jesús Tamariz   +4 more
doaj   +1 more source