Results 71 to 80 of about 38,099 (221)

The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes [PDF]

, 2007
Context: Obesity-associated inflammation is a contributory factor in the pathogenesis of type 2 diabetes mellitus (T2DM); the mechanisms underlying the progression to T2DM are unclear.
Adam R. Baker, Alison L. Harte, Aranda, Asensio, Baan, Banerjee, Bokarewa, Borst, Bradford, Christine M. Kusminski, Creely, Curat, Einstein, Ffolliott M. Fisher, Fu, Graveleau, Hirosumi, Hotamisligil, Kusminski, Lehrke, Li, Lin, McTernan, McTernan, Nancy F. da Silva, Pagano, Patel, Philip G. McTernan, Rae, Rajala, Rajala, Rangwala, Reilly, Ridker, Roeder, Sato, Savage, Shetty, Silswal, Steppan, Steppan, Steven J. Creely, Sudhesh Kumar, Tzou, Weisberg, Xu   +45 more
core   +1 more source

Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler, Klara R. Klein, Ildiko Lingvay, Anthony Pick, Liana K. Billings   +4 more
wiley   +1 more source

Serum Resistin levels in bladder cancer

Men's Health Journal, 2018
Background: Adipokines play a role in pathogenesis and progression of certain cancers. Resistin is an adipokine with diverse findings in disease development and progression.
Mahmoud Mohammadi, Jalil Hosseini, Morteza Fallah Karkan, Mehdi Hedayati   +3 more
doaj   +1 more source

Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndrome [PDF]

, 2015
Diabetes and metabolic syndrome are associated with abnormal postprandial lipoprotein metabolism, with a significant delay in the clearance of many lipid parameters, including triglycerides and chylomicrons.
ARCA, Marcello
core   +1 more source

MiRNAs as novel adipokines : obesity-related circulating MiRNAs influence chemosensitivity in cancer patients [PDF]

, 2020
Adipose tissue is an endocrine organ, capable of regulating distant physiological processes in other tissues via the release of adipokines into the bloodstream.
Dewhurst, T, Hammond, CJ, Topham, CH, Withers, SB   +3 more
core   +2 more sources

Muscle Mass Is a Better Predictor of Survival in Dogs With Chronic Kidney Disease Compared to Body Condition Score

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Monitoring prognostic factors, such as body weight, is important to assess the effectiveness of therapies in patients with chronic kidney disease (CKD) and estimate the survival rate (SR). As established in the literature, both body condition score (BCS) and muscle mass score (MMS), when analysed individually, show a positive correlation with ...
Thiago Henrique Annibale Vendramini, Pedro Henrique Marchi, Vivian Pedrinelli, Andressa Rodrigues Amaral, Laís Oyama Cotrim Lima, Bianca Petermann Moretti, Natália Manuela Cardoso de Oliveira, Cristiana F. F. Pontieri, Juliana T. Jeremias, Júlio Cesar de Carvalho Balieiro, Marcio Antonio Brunetto   +10 more
wiley   +1 more source

Response to ‘Resistin letters’ [PDF]

Kidney International, 2006
We thank Fagerberg et al. for their contribution to the growing body of evidence refuting a causative relationship between the protein resistin and insulin resistance in man.1 Indeed, resistin was first described as found in inflammatory zone (FIZZ)-1, indicating its structural similarity to several other proinflammatory cytokines.2 Indeed, resistin is
Axelsson, J., Lindholm, B., Stenvinkel, P.   +2 more
openaire   +1 more source

Resistin Is Increased in Periodontal Cells and Tissues: In Vitro and In Vivo Studies

Mediators of Inflammation, 2020
Resistin, a proinflammatory adipokine, is elevated in many inflammatory diseases. However, little is known about its performance in periodontitis. The present study is aimed at evaluating resistin expression and synthesis in periodontal cells and tissues
Andressa V. B. Nogueira, Marjan Nokhbehsaim, Sema Tekin, Rafael S. de Molon, Luis C. Spolidorio, Svenja Memmert, Anna Damanaki, Andreas Jäger, Sigrun Eick, James Deschner, Joni A. Cirelli   +10 more
doaj   +1 more source

Suppressor of Cytokine Signaling-3 (SOCS-3) induces Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) expression in hepatic HepG2 cell line [PDF]

, 2015
The suppressor of cytokine signaling (SOCS) proteins are negative regulators of the JAK/STAT pathway activated by proinflammatory cytokines, including the tumor necrosis factor (TNF-\u3b1).
Corsini, Alberto, Cristofani, Riccardo, Ferri, Nicola, Liu, Jingwen, Macchi, Chiara, Magni, Paolo, Ricci, Chiara, Ruscica, Massimiliano   +7 more
core   +2 more sources

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source