Results 91 to 100 of about 3,694,925 (238)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Detector physics of resistive plate chambers [PDF]

open access: yes, 2002
Resistive Plate Chambers (RPCs) are gaseous parallel plate avalanche detectors that implement electrodes made from a material with a high volume resistivity between 10 high 7 and 10 high 12 omega cm.
Lippmann, Christian, Lippmann, C
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Renal resistive index: Beyond the hemodynamics

open access: yes, 2020
We read with great interest the original article entitled “Prognostic significance of the renal resistive index in the primary prevention of type II diabetes” by Delsart et al1 In this issue of The Journal, the authors interestingly underlined the ...
Mule G.   +3 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Averaged Resistive MHD Equations

open access: yes, 1993
Averaged resistive MHD equations are derived by using the Lagrangian formalism. The assumption is that the perturbation is of single toroidal harmonics on the special magnetic coordinates Jacobian of which is independent of the toroidal angle.
"Todoroki, J."
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Portal Vein and Hepatic Artery Doppler Indices in Non-Alcoholic Fatty Liver Disease: Relationship with Ultrasonographic Steatosis Grading.

open access: yesMinia Journal of Medical Research
Background: Non-alcoholic fatty liver disease is commonly detected and graded by grayscale ultrasonography; however, conventional ultrasound provides limited information about hepatic hemodynamic changes.
Nadia Mohammed Elamen   +2 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Significance and Diagnostic Accuracy of Resistive Index in Predicting Malignant Ovarian Masses Keeping Histopathology as Gold Standard

open access: yesJournal of Gandhara Medical and Dental Sciences
OBJECTIVE This study aimed to determine the significance and diagnostic accuracy of the resistive index (RI) in predicting malignancy in ovarian masses, using histopathology as the gold standard. METHODOLOGY This prospective study was conducted at
Sana Iqbal, Anam Safdar, Shandana khan
doaj   +1 more source

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