IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Percolation-Induced Electrical Conductivity in Bio-Based Shape Memory Polybenzoxazine/Polycaprolactone Composites Reinforced with Carbon Black. [PDF]
Chaipakdee N +5 more
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Investigation of the Physical Properties of Poly(ester-ether)s and Multi-Walled Carbon Nanotube Nanocomposites. [PDF]
Guidotti G +7 more
europepmc +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Influence of 3D Printing Parameters on Apparent Resistivity, Repeatability and Time-Dependent Drift of Conductive PLA. [PDF]
Popescu D +3 more
europepmc +1 more source
Precursor-Dependent Performance of FA-, GBFS-, MK- and WBP-Based Geopolymer Mortars: Effects of NaOH Molarity and Thermal Curing on Strength, Transport Properties and Cost Efficiency. [PDF]
Çelik DN +3 more
europepmc +1 more source
A sample holder system for high-precision and reliable resistivity measurements of laboratory lime-cement samples. [PDF]
Lumetzberger M +5 more
europepmc +1 more source
Observation of thermally stable polar metallic state in perovskite nitride CeWN<sub>3</sub>. [PDF]
Ye X +16 more
europepmc +1 more source

