Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Optimized SnO<sub>2</sub> Thin Films: Correlating Solution Chemistry and Deposition Conditions with Optoelectronic Properties. [PDF]
Ramzan I +3 more
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Study on the combined influence mechanism of temperature, density and moisture content on the resistivity of loess. [PDF]
Bi Y, Cui B, Li S, Fan N, Gu T, Feng R.
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Solidification of Lead Ions Through Supersulfated Cement: Hydration and Mechanisms. [PDF]
Deng F +9 more
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Integration of ERT and Geotechnical Investigation for River Restoration: A Case Study of Dam Removal Site Characterization. [PDF]
Rahimi M +5 more
europepmc +1 more source
High-Temperature Stable Amorphous Al<sub>2-<i>x</i></sub>(ZrY)<sub><i>x</i></sub>O<sub>3</sub> Thin Film Insulators: An Alternative to Crystalline Alumina. [PDF]
Salvadores Farran N +11 more
europepmc +1 more source

