Results 191 to 200 of about 4,279,285 (309)

Quantification of the Tissue Sodium Concentration in the Human Calf at 7T With Reduced Acquisition Time: Influence of the Nominal Spatial Resolution. [PDF]

NMR Biomed
Höhn JM, Wilferth T, Gast LV, Gerhalter T, Kopp C, Uder M, Nagel AM.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Author Correction: Central American mountains inhibit eastern North Pacific seasonal tropical cyclone activity

Nature Communications
Dan Fu, Ping Chang, Christina M. Patricola-DiRosario, R. Saravanan, Xue Liu, Hylke E. Beck   +5 more
doaj   +1 more source

Task-based evaluation of axial and multiplanar reconstructions in computed tomography: A volumetric analysis of spatial resolution, noise, and detectability. [PDF]

J Appl Clin Med Phys
Monnin P, Viry A, Becce F, Racine D.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Monte Carlo simulation and experimental validation of SPECT systems via energy spectrum decomposition and image profile analysis. [PDF]

EJNMMI Phys
Peng Z, Wasaye MA, Siddique I, Wali F, Saeed M.   +4 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Python-controlled multimodal UV-VIS hyperspectral imaging system. [PDF]

J Biomed Opt
Bullard EA, Stout EM, Benavides OR, Bawiskar A, Singh L, Vu NN, Mabbott S, Walsh AJ.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Advances in the Design and Functionality of a Compact Multi-Reflecting Time-of-Flight Mass Spectrometer. [PDF]

Rapid Commun Mass Spectrom
Wildgoose J, Ferries S, Gethings LA, Daly ME, Palmer ME, Lock R, Vissers JPC, Langridge JI.   +7 more
europepmc   +1 more source