Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Super-resolution microscopy: revolutionizing life sciences through advanced resolution. [PDF]
Biophys RepLuo S, Dong Y, Gu L, Ji W.
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
The Clinical Relevance of the Rectosigmoid Brake in Surgical Disorders and Therapies: A Systematic Review of Colonic Manometry Studies. [PDF]
Neurogastroenterol MotilPenfold JA +3 more
europepmc +1 more source
Scaffolds with optimized quaternary symmetry for de novo cryoEM structure determination of small RNAs. [PDF]
Nat MethodsJones CP, Ferré-D'Amaré AR.
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Corrigendum to "Multiple Treatment Analysis of Aneurysmal Bone Cysts in Mobile Spine". [PDF]
Global Spine Jeuropepmc +1 more source
HiCMamba: Enhancing Hi-C resolution and identifying 3D genome structures with state space modeling. [PDF]
PLoS Comput BiolYang M +7 more
europepmc +1 more source
Super-resolution functional photoacoustic microscopy via label-free cell tracking. [PDF]
Light Sci ApplZhong F +9 more
europepmc +1 more source