Results 61 to 70 of about 4,444,880 (307)

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

The effect of race, gender and priming on LLMs’ conviction predictions

Humanities & Social Sciences Communications
Large Language Models (LLMs) could help overcome fundamental shortcomings in justice systems, by enhancing access to justice, supporting legal professionals, and ultimately promoting fairness and efficiency across legal frameworks.
Talia Schwartz, Chen Wang
doaj   +1 more source

High-resolution digital holography utilized by the subpixel sampling method [PDF]

, 2011
A novel (to our knowledge) approach for resolution improvement in digital holography is presented in this paper. The proposed method is based on recording the incoming interference field on a complementary metal-oxide semiconductor (CMOS) camera with ...
Fritzsche, Marco, Bryanston-Cross, P., Timmerman, B. H. (Brenda H.), Peter Bryanston-Cross, Claus, Daniel, Daniel Claus, Daciana Iliescu, Brenda Timmerman, Iliescu, Daciana, Marco Fritzsche   +9 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A European Deposit Insurance and Resolution Fund. CEPS Working Document No. 364, 10 May 2012 [PDF]

, 2012
The eurozone is caught in a ‘diabolical loop’ in which weak domestic banking systems damage sovereign fiscal positions and conversely, in which risky sovereign positions disproportionately threaten domestic banking stability.
Schoenmaker, Dirk, Gros, Daniel
core  

Low-resolution human pose estimation

, 2022
Human pose estimation has achieved significant progress on images with high imaging resolution. However, low-resolution imagery data bring nontrivial challenges which are still under-studied. To fill this gap, we start with investigating existing methods
Ge, Shuzhi, Zhang, Feng, ZHU, XIATIAN, Wang, Chen, Shuzhi Sam Ge, Feng Zhang, Chen Wang, Xiatian Zhu   +7 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

PM2.5 Concentration Estimation in Single Hazy Images Using Luminance–Spatial Decoupling

Remote Sensing
Image-based PM2.5 estimation has emerged as a promising complementary approach to traditional physicochemical monitoring. However, achieving accurate predictions in severely polluted environments remains a critical challenge, as existing deep learning ...
Runjie Wang, Yuhang Liu, Xianglei Liu, Yahao Wu   +3 more
doaj   +1 more source