Results 31 to 40 of about 2,655,411 (248)
Time-to-Digital Converter IP-Core for FPGA at State of the Art
IEEE Access, 2021 The Field Programmable Gate Array (FPGA) structure poses several constraints that make the implementation of complex asynchronous circuits such as Time–Mode (TM) circuits almost unfeasible.
Fabio Garzetti +3 more
doaj +1 more source
Ten Theses on Logic Languages for the Semantic Web [PDF]
, 2005 This articles discusses the logic, or logic-based, languages required for a full deployment of the SemanticWeb. It presents ten theses addressing 1. the kinds of logic languages needed, 2. data and data processing, 3. semantics, and 4.
Massimo Marchiori +4 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
A second order logic of existence [PDF]
, 1969 Publisher's, offprint versionA. N. Prior in [9] has suggested an approach towards a second order logic of existence where, following medieval logicians, we distinguish “between predicates (like ‘is red’, ‘is hard’, etc.) which entail existence, and ...
Cocchiarella, Nino
core +1 more source
A new redundancy resolution for underwater vehicle–manipulator system considering payload
International Journal of Advanced Robotic Systems, 2017 For the motion coordination problem between the underwater vehicle and manipulator of the underwater vehicle–manipulator system, a new redundancy resolution method is proposed and investigated. The proposed method mainly has two parts: a fuzzy logic part
Yaoyao Wang +4 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
The road to modern logic - an interpretation [PDF]
, 2001 This paper aims to outline an analysis and interpretation of the process that led to First-Order Logic and its consolidation as a core system of modern logic.
Ferreirós Domínguez, José Manuel
core +1 more source